Apoptosis

Ac-VDVAD-pNA is a colorimetric substrate for caspase-2.

Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM).

Carfilzomib impurity 13 (hydrochloride) is a potential impurity found in commercial carfilzomib preparations.

Caspase-9 inhibitor III is an inhibitor of caspase-9 with cardioprotective effects.

CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP.

Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling.

Daphnoretin is a coumarin that has been found in W.

Didymin is a flavonoid that has been found in citrus fruits with diverse biological activities.

Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals.

The phosphatidylinositol 3-kinase (PI3K)/Akt signal transduction pathway plays critical roles in cell growth and proliferation making it an attractive target for anticancer agents.

Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks.

Endothelin-1 is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively).

GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption.

L-threo-PPMP is an inhibitor of glucosylceramide synthetase and isomer of D-threo-PPMP.

Mca-VDQMDGW-K(Dnp)-NH2 is a substrate for caspase-3.

p,p'-DDT is an organochlorine pesticide that induces 94.2% mortality of malaria mosquito (A.

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase.

Z-DEVD-CMK is a protease inhibitor.

Z-VDVAD-AFC is a fluorogenic substrate for caspase-2.

Z-VDVAD-pNA is a colorimetric substrate for caspase-2.

Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3.

A neuropeptide with diverse biological activities

A neuropeptide with diverse biological activities