CPTH6 (hydrobromide) |
| Katalog-Nr.GC43321 |
CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2321332-57-2
Sample solution is provided at 25 µL, 10mM.
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CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP. It blocks the acetylation of H3/H4 histones and α-tubulin in several leukemia cell lines. CPTH6 reduces cell viability, arresting cell cycling in the G0/G1 phase and inducing apoptosis. It impairs autophagy in a variety of tumor cell lines, at least in part by altering ATG7-mediated elongation of autophagosomal membranes.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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