Z-YVAD-CMK (trifluoroacetate salt) (Synonyms: Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV) |
| Katalog-Nr.GC45193 |
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3. It reduces IL-1β and IL-18 secretion in isolated mouse peritoneal macrophages stimulated by cholesterol-treated recombinant pneumolysin protein (rPLY) when used at a concentration of 30 µM. Z-YVAD-CMK reduces caspase-3 activation by the EGF-like domain of tenascin-C in detached human smooth muscle cells (hSMCs) in vitro. It also decreases cell death induced by the EGF-like domain of tenascin-C by 50% when used at a concentration of 100 µM in hSMCs and completely inhibits cell death at concentrations ranging from 200 to 400 µM.
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *