GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(553)

  • GC40627 structure
    GC40627tetranor-Misoprostol
    Purity: >95.00%

    tetranor-Misoprostol is a metabolite of misoprostol.

  • GC40675 structure
    GC406752-deoxy-Artemisinin
    CAS: 72826-63-2
    Purity: >98.00%

    2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.

  • GC40834 structure
    GC40834cis-Entacapone
    CAS: 145195-63-7
    Purity: >98.00%

    cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone.

  • GC40852 structure
    GC40852N-Demethylerythromycin A
    CAS: 992-62-1
    Purity: >95.00%

    N-Demethylerythromycin A is a metabolite of erythromycin.

  • GC40879 structure
    GC408794-hydroxy Solifenacin N-oxide
    CAS: 2747991-39-3
    Purity: >95.00%

    4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .

  • GC40968 structure
    GC4096821-hydroxy Eplerenone
    CAS: 334678-67-0
    Purity: >98.00%

    21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.

  • GC41154 structure
    GC411542-keto-D-Glucose
    CAS: 1854-25-7
    Purity: >95.00%

    2-Keto-D-Glucose (D-Glucoson) ist ein wichtiges Zwischenprodukt in einem sekundÄren Stoffwechselweg, der zum Antibiotikum Cortalceron fÜhrt.

  • GC41177 structure
    GC41177Lurasidone metabolite 14283
    CAS: 186204-31-9
    Purity: >95.00%

    Lurasidone metabolite 14283 is an active metabolite of the atypical antipsychotic lurasidone .

  • GC41249 structure
    GC41249p,p'-DDD
    CAS: 72-54-8
    Purity: >98.00%

    p,p'-DDD ist ein Hauptmetabolit von p,p'-DDT.

  • GC41266 structure
    GC41266Pregnanediol-3-Glucuronide
    CAS: 1852-49-9
    Purity: >95.00%

    Pregnanediol-3-Glucuronid ist der wichtigste Endmetabolit von Progesteron und spielt eine wichtige Rolle bei physiologischen Prozessen wie dem weiblichen Menstruationszyklus, der Schwangerschaft (unterstützt die Schwangerschaft), der Embryogenese und der mütterlichen Immunantwort von Menschen und anderen Spezies.

  • GC41270 structure
    GC41270N-desmethyl Zolmitriptan
    CAS: 139264-35-0
    Purity: >95.00%

    N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan.

  • GC41300 structure
    GC4130017β-hydroxy Exemestane
    CAS: 122370-91-6
    Purity: >98.00%

    17β-hydroxy Exemestane is the primary active metabolite of exemestane.

  • GC41309 structure
    GC4130916α-hydroxy Prednisolone
    CAS: 13951-70-7
    Purity: >98.00%

    16α-Hydroxy-Prednisolon ist ein stereoselektiver Metabolit des 22(R)-Epimers des Glukokortikoids Budesonid Über Cytochrom P450 3A (CYP3A)-Enzyme.

  • GC41312 structure
    GC413125-hydroxy Omeprazole
    CAS: 92340-57-3
    Purity: >98.00%

    5-hydroxy Omeprazole is a major metabolite of omeprazole, an inhibitor of the gastric H+/K+-ATPase pump.

  • GC41315 structure
    GC41315(±)-Ketoprofen Glucuronide
    CAS: 76690-94-3
    Purity: >95.00%

    (±)-Ketoprofen glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen.

  • GC41325 structure
    GC41325Mycophenolic Acid β-D-Glucuronide
    CAS: 31528-44-6
    Purity: >98.00%

    MycophenolsÄure β-D-Glucuronid ist ein Metabolit des Immunsuppressivums MycophenolsÄure (MPA). MycophenolsÄure β-D-Glucuronid zeigt AntitumoraktivitÄt und kann in der Adenokarzinomforschung verwendet werden.

  • GC41339 structure
    GC41339Pioglitazone Ketone
    CAS: 146062-45-5
    Purity: >98.00%

    Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone.

  • GC41380 structure
    GC41380N-desmethyl Rosiglitazone
    CAS: 257892-31-2
    Purity: >98.00%

    N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone, a potent and selective PPARγ ligand present in formulations that have been used to treat type 2 diabetes.

  • GC41399 structure
    GC413995α-dihydro Levonorgestrel
    CAS: 78088-19-4
    Purity: >95.00%

    5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel.

  • GC41480 structure
    GC414803'-hydroxy Lidocaine
    CAS: 34604-55-2
    Purity: >98.00%

    3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4.

  • GC41565 structure
    GC415653-hydroxy Medetomidine
    CAS: 128366-50-7
    Purity: >95.00%

    3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine.

  • GC41661 structure
    GC41661(±)-4-hydroxy Propranolol β-D-Glucuronide
    CAS: 94731-13-2
    Purity: >90.00%

    (±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.

  • GC41671 structure
    GC41671(±)-Equol 4'-sulfate (sodium salt)
    CAS: 1189685-28-6
    Purity: >90.00%

    (±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.

  • GC41694 structure
    GC41694(3S)-hydroxy Quinidine
    CAS: 53467-23-5
    Purity: >98.00%

    (3S)-hydroxy Quinidine is an active quinidine metabolite.