Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(546)
- GC43493DL-Sulforaphane N-acetyl-L-cysteineCAS: 334829-66-2Purity: >98.00%
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress.
- GC43565Doxorubicinol (hydrochloride)CAS: 63950-05-0Purity: >90.00%
Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks.
- GC43646Ezetimibe Hydroxy GlucuronideCAS: 536709-33-8Purity: >95.00%
Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe .
- GC43675Florfenicol amine (hydrochloride)CAS: 108656-33-3Purity: >95.00%
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine.
- GC43697Formoterol O-β-D-GlucuronideCAS: 615551-59-2Purity: >95.00%
Formoterol O-β-D-glucuronide is a metabolite of formoterol .
- GC43743Gemfibrozil 1-O-β-GlucuronideCAS: 91683-38-4Purity: >99.5%
Gemfibrozil 1-O-β-Glucuronid, ein Metabolit von Gemfibrozil, ist ein potenter und kompetitiver P450 (CYP)-Isoform-CYP2C8-Inhibitor mit einem IC50 von 4,07 μM.
- GC43878Hydroxy DimetridazoleCAS: 936-05-0Purity: >98.50%
Hydroxydimetridazol (Hydroxydimetridazol) ist ein Hydroxymetabolit von Dimetridazol.
- GC43895Iloperidone metabolite P88CAS: 133454-55-4Purity: >99.50%
Iloperidon-Metabolit P88 (P88; Hydroxy-Iloperidon) ist ein Metabolit von Iloperidon, einem atypischen Antipsychotikum.
- GC43896Iloperidone metabolite P95CAS: 475110-48-6Purity: >98.00%
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone.
- GC44033Lansoprazole sulfoneCAS: 131926-99-3Purity: >98.00%
Lansoprazole sulfone is a phase I metabolite of lansoprazole.
- GC44246Moxifloxacin N-Sulfate (sodium salt)Purity: >95.00%
Moxifloxacin N-sulfate is a metabolite of moxifloxacin.
- GC44294N-acetyl DapsoneCAS: 565-20-8Purity: >95.00%
N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders.
- GC44299N-Acetyl-4-benzoquinone imineCAS: 50700-49-7Purity: >90.00%
N-Acetyl-4-benzochinonimin ist der toxische Metabolit von Acetaminophen.
- GC44304N-Acetyl-S-allyl-L-cysteineCAS: 23127-41-5Purity: >98.00%
L-Deoxyalliin, also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.
- GC44345N-Desethyl VardenafilCAS: 448184-46-1Purity: >98.00%
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.
- GC44348N-desmethyl BendamustineCAS: 41515-13-3Purity: >95.00%
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine.
- GC44349N-desmethyl LevofloxacinCAS: 117707-40-1Purity: >98.00%
N-Desmethyl Levofloxacin ist ein Metabolit von Levofloxacin.
- GC44350N-Desmethyl SildenafilCAS: 139755-82-1Purity: >98.00%
N-Desmethyl Sildenafil (Desmethylsildenafil) ist ein Hauptmetabolit von Sildenafil.
- GC44351N-Desmethyl Sildenafil (citrate)Purity: >98.00%
N-Desmethyl sildenafil is a major metabolite of sildenafil.
- GC44358Nebivolol O-β-D-GlucuronidePurity: >95.00%
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.
- GC44451Norfluoxetine (hydrochloride)CAS: 57226-68-3Purity: >98.00%
Norfluoxetin (Hydrochlorid) ist ein aktiver N-demethylierter Metabolit von Fluoxetin.
- GC44492O-Desmethyl MetoprololCAS: 62572-94-5Purity: >99.00%
O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC43493 | DL-Sulforaphane N-acetyl-L-cysteine | 334829-66-2 | >98.00% | |
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. | ||||
| GC43565 | Doxorubicinol (hydrochloride) | 63950-05-0 | >90.00% | |
Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. | ||||
| GC43646 | Ezetimibe Hydroxy Glucuronide | 536709-33-8 | >95.00% | |
Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe . | ||||
| GC43675 | Florfenicol amine (hydrochloride) | 108656-33-3 | >95.00% | |
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine. | ||||
| GC43697 | Formoterol O-β-D-Glucuronide | 615551-59-2 | >95.00% | |
Formoterol O-β-D-glucuronide is a metabolite of formoterol . | ||||
| GC43743 | Gemfibrozil 1-O-β-Glucuronide | 91683-38-4 | >99.5% | |
Gemfibrozil 1-O-β-Glucuronid, ein Metabolit von Gemfibrozil, ist ein potenter und kompetitiver P450 (CYP)-Isoform-CYP2C8-Inhibitor mit einem IC50 von 4,07 μM. | ||||
| GC43878 | Hydroxy Dimetridazole | 936-05-0 | >98.50% | |
Hydroxydimetridazol (Hydroxydimetridazol) ist ein Hydroxymetabolit von Dimetridazol. | ||||
| GC43879 | Hydroxy Ebastine | 210686-41-2 | >87.00% | |
Hydroxy Ebastine is an ebastine metabolite. | ||||
| GC43881 | Hydroxy Varenicline | 357424-21-6 | >95.00% | |
A metabolite of varenicline | ||||
| GC43895 | Iloperidone metabolite P88 | 133454-55-4 | >99.50% | |
Iloperidon-Metabolit P88 (P88; Hydroxy-Iloperidon) ist ein Metabolit von Iloperidon, einem atypischen Antipsychotikum. | ||||
| GC43896 | Iloperidone metabolite P95 | 475110-48-6 | >98.00% | |
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. | ||||
| GC44033 | Lansoprazole sulfone | 131926-99-3 | >98.00% | |
Lansoprazole sulfone is a phase I metabolite of lansoprazole. | ||||
| GC44246 | Moxifloxacin N-Sulfate (sodium salt) | - | >95.00% | |
Moxifloxacin N-sulfate is a metabolite of moxifloxacin. | ||||
| GC44294 | N-acetyl Dapsone | 565-20-8 | >95.00% | |
N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. | ||||
| GC44299 | N-Acetyl-4-benzoquinone imine | 50700-49-7 | >90.00% | |
N-Acetyl-4-benzochinonimin ist der toxische Metabolit von Acetaminophen. | ||||
| GC44304 | N-Acetyl-S-allyl-L-cysteine | 23127-41-5 | >98.00% | |
L-Deoxyalliin, also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities. | ||||
| GC44345 | N-Desethyl Vardenafil | 448184-46-1 | >98.00% | |
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5. | ||||
| GC44348 | N-desmethyl Bendamustine | 41515-13-3 | >95.00% | |
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine. | ||||
| GC44349 | N-desmethyl Levofloxacin | 117707-40-1 | >98.00% | |
N-Desmethyl Levofloxacin ist ein Metabolit von Levofloxacin. | ||||
| GC44350 | N-Desmethyl Sildenafil | 139755-82-1 | >98.00% | |
N-Desmethyl Sildenafil (Desmethylsildenafil) ist ein Hauptmetabolit von Sildenafil. | ||||
| GC44351 | N-Desmethyl Sildenafil (citrate) | - | >98.00% | |
N-Desmethyl sildenafil is a major metabolite of sildenafil. | ||||
| GC44358 | Nebivolol O-β-D-Glucuronide | - | >95.00% | |
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol. | ||||
| GC44451 | Norfluoxetine (hydrochloride) | 57226-68-3 | >98.00% | |
Norfluoxetin (Hydrochlorid) ist ein aktiver N-demethylierter Metabolit von Fluoxetin. | ||||
| GC44492 | O-Desmethyl Metoprolol | 62572-94-5 | >99.00% | |
O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol. | ||||