Iloperidone metabolite P88 (Synonyms: P88-8991) |
Katalog-Nr.GC43895 |
Iloperidon-Metabolit P88 (P88; Hydroxy-Iloperidon) ist ein Metabolit von Iloperidon, einem atypischen Antipsychotikum.
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Cas No.: 133454-55-4
Sample solution is provided at 25 µL, 10mM.
Iloperidone metabolite P88 is an active metabolite of the atypical antipsychotic iloperidone . It binds to the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, and 5-HT2C (Kis = 5.1, 0.03, and 6.9 nM, respectively), α2b- and α2c-adrenergic (Kis = 6 and 1.3 nM, respectively), and dopamine D1, D2A, and D4 receptors (Kis = 9.5, 1.6, and 3.5 nM, respectively).
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