BI-4464 |
| Catalog No.GC34488 |
Le BI-4464 est un inhibiteur compétitif de l'ATP hautement sélectif de PTK2/FAK, avec une IC50 de 17 nM. Un ligand PTK2 pour PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1227948-02-8
Sample solution is provided at 25 µL, 10mM.
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BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC[1]. IC50: 17 nM (PTK2/FAK)[1].
[1]. Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62(5):2508-2520.
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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