ZED-1227 |
| Catalog No.GC37963 |
ZED-1227 est un inhibiteur spécifique et oralement actif de la transglutaminase 2 (TG2), avec une IC50 de 45 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1542132-88-6
Sample solution is provided at 25 µL, 10mM.
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ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1]. TG2[1]
[1]. Manu Encalada, et al. The Oral Transglutaminase 2 (TG2) Inhibitor Zed1227 Blocks TG2 Activity in a Mouse Model of Intestinal Inflammation. Gastroenterology. 154(6):S-490.
Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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