Innate Immunity
Products Related to Innate Immunity(566)
- GC44590PellitorineCAS: 18836-52-7Purity: >98.00%
La pellitorine est un composé isolé des racines de Piper nigrum. La pellitorine présente de fortes activités cytotoxiques contre les lignées cellulaires HL60 et MCT-7. Pellitorine a le potentiel pour la recherche de maladies cancéreuses.
- GC44633Phosphatidylserines (bovine)CAS: 1446756-47-3Purity: >98.00%
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.
- GC44696Prolyl-glycyl-proline PeptidePurity: >95.00%
Proline-glycine-proline (PGP) is a tripeptide molecule and an established biomarker for chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF).
- GC44794PyrrophenoneCAS: 341973-06-6Purity: >99.50%
La pyrrophénone est un inhibiteur puissant et spécifique de la phospholipase cytosolique A2α (cPLA2α) avec une valeur IC50 de 4,2 nM.
- GC44818Resolvin D4CAS: 1025684-60-9Purity: >95.00%
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.
- GC44820Resveratrol-3-O-Sulfate (sodium salt)CAS: 858127-11-4Purity: >95.00%
Le resvératrol-3-O-sulfate (sodium) est le métabolite du resvératrol.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
La rosiglitazone (BRL 49653) potassique est un PPARγ sélectif actif par voie orale; agoniste (EC50 : 60 nM, Kd : 40 nM).
- GC44910Sodium Hydrogen Sulfide (hydrate)CAS: 207683-19-0Purity: >68.00%
Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.
- GC44919SP 600125, negative controlCAS: 54642-23-8Purity: >99.50%
SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.
- GC44930Sphingosine (d14:1)CAS: 24558-60-9Purity: >98.00%
La sphingosine (d14:1) (Tetradecasphing-4-enine), un sphingolipide, est un puissant inhibiteur de la protéine kinase C (PKC). La sphingosine (d14:1) empêche son interaction avec les esters de sn-1,2-diacylglycérol (DAG)/Phorbol.
- GC44956StreptochlorinCAS: 120191-51-7Purity: >98.00%
Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp.
- GC44999Tauro-α-muricholic Acid (sodium salt)CAS: 2260905-08-4Purity: >95.00%
Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid.
- GC45004TC 14012 (trifluoroacetate salt)Purity: >95.00%
C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12).
- GC45012Tenofovir diphosphate (sodium salt)Purity: >95.00%
Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM).
- GC45063Toll-Like Receptor 7 Ligand IICAS: 226907-52-4Purity: >98.00%
Toll-Like Receptor 7 Ligand II (CL-087) est un puissant agoniste oral actif du TLR7.
- GC45146VIP (human, porcine, rat, ovine) (trifluoroacetate salt)Purity: >98.00%
Vasoactive intestinal peptide (VIP) is a peptide that acts as a neurotransmitter and hormone.
- GC45154W140 (trifluoroacetate salt)CAS: 909725-64-0Purity: >95.00%
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.
- GC45155W146 (trifluoroacetate salt)CAS: 909725-62-8Purity: >95.00%
W146 (trifluoroacetate salt) est un antagoniste sélectif des récepteurs de la sphingosine 1-phosphate de type 1 (S1PR1), sa valeur d'EC50 est 398nM.
- GC45193Z-YVAD-CMK (trifluoroacetate salt)Purity: >95.00%
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44590 | Pellitorine | 18836-52-7 | >98.00% | |
La pellitorine est un composé isolé des racines de Piper nigrum. La pellitorine présente de fortes activités cytotoxiques contre les lignées cellulaires HL60 et MCT-7. Pellitorine a le potentiel pour la recherche de maladies cancéreuses. | ||||
| GC44633 | Phosphatidylserines (bovine) | 1446756-47-3 | >98.00% | |
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. | ||||
| GC44696 | Prolyl-glycyl-proline Peptide | - | >95.00% | |
Proline-glycine-proline (PGP) is a tripeptide molecule and an established biomarker for chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). | ||||
| GC44794 | Pyrrophenone | 341973-06-6 | >99.50% | |
La pyrrophénone est un inhibiteur puissant et spécifique de la phospholipase cytosolique A2α (cPLA2α) avec une valeur IC50 de 4,2 nM. | ||||
| GC44802 | R-8507 | 338773-13-0 | >98.00% | |
R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI). | ||||
| GC44818 | Resolvin D4 | 1025684-60-9 | >95.00% | |
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid. | ||||
| GC44820 | Resveratrol-3-O-Sulfate (sodium salt) | 858127-11-4 | >95.00% | |
Le resvératrol-3-O-sulfate (sodium) est le métabolite du resvératrol. | ||||
| GC44839 | Ridaifen-B | 886465-70-9 | >98.00% | |
An analog of tamoxifen | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
La rosiglitazone (BRL 49653) potassique est un PPARγ sélectif actif par voie orale; agoniste (EC50 : 60 nM, Kd : 40 nM). | ||||
| GC44910 | Sodium Hydrogen Sulfide (hydrate) | 207683-19-0 | >68.00% | |
Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. | ||||
| GC44919 | SP 600125, negative control | 54642-23-8 | >99.50% | |
SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM. | ||||
| GC44930 | Sphingosine (d14:1) | 24558-60-9 | >98.00% | |
La sphingosine (d14:1) (Tetradecasphing-4-enine), un sphingolipide, est un puissant inhibiteur de la protéine kinase C (PKC). La sphingosine (d14:1) empêche son interaction avec les esters de sn-1,2-diacylglycérol (DAG)/Phorbol. | ||||
| GC44948 | StA-IFN-1 | 300839-31-0 | >98.00% | |
StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway. | ||||
| GC44956 | Streptochlorin | 120191-51-7 | >98.00% | |
Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp. | ||||
| GC44999 | Tauro-α-muricholic Acid (sodium salt) | 2260905-08-4 | >95.00% | |
Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid. | ||||
| GC45004 | TC 14012 (trifluoroacetate salt) | - | >95.00% | |
C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12). | ||||
| GC45012 | Tenofovir diphosphate (sodium salt) | - | >95.00% | |
Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). | ||||
| GC45030 | TG6-129 | 1164464-14-5 | >98.00% | |
TG6-129 est un antagoniste sélectif du récepteur EP2. | ||||
| GC45057 | TIQ-A | 420849-22-5 | >98.00% | |
TIQ-A est un puissant inhibiteur de TNKS (poly-ART, PARP), avec une IC50 de 24 nM pour TNKS2. | ||||
| GC45063 | Toll-Like Receptor 7 Ligand II | 226907-52-4 | >98.00% | |
Toll-Like Receptor 7 Ligand II (CL-087) est un puissant agoniste oral actif du TLR7. | ||||
| GC45146 | VIP (human, porcine, rat, ovine) (trifluoroacetate salt) | - | >98.00% | |
Vasoactive intestinal peptide (VIP) is a peptide that acts as a neurotransmitter and hormone. | ||||
| GC45154 | W140 (trifluoroacetate salt) | 909725-64-0 | >95.00% | |
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. | ||||
| GC45155 | W146 (trifluoroacetate salt) | 909725-62-8 | >95.00% | |
W146 (trifluoroacetate salt) est un antagoniste sélectif des récepteurs de la sphingosine 1-phosphate de type 1 (S1PR1), sa valeur d'EC50 est 398nM. | ||||
| GC45193 | Z-YVAD-CMK (trifluoroacetate salt) | - | >95.00% | |
Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3. | ||||