FGFR
FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.
Products Related to FGFR(109)
- GC73852Infigratinib-BocCAS: 2504949-83-9Purity: >98.00%
Infigratinib-Boc est un dérivé de l’infigratinib contenant un groupe Boc (t-Butyloxy carbonyl).
- GC74365VSPPLTLGQLLSCAS: 1206896-24-3Purity: >98.00%
VSPPLTLGQLLS est un petit inhibiteur du peptide fgfr3, le Peptide P3, qui inhibe la phosphorylation du fgfr3.
- GC813192,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucroseCAS: 150302-84-4Purity: >98%
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica.
- GC81325VEGFR2-IN-84CAS: 861877-12-5Purity: >98%
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold.
- GC81329TCB-32 hydrochlorideCAS: 169764-95-8Purity: >97.50%
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.
- GN10527FormononetinCAS: 485-72-3Purity: >99.50%
Formononetin est un puissant inhibiteur de FGFR2, sa valeur d'IC50 est 4,3μM. Formononetin inhibe efficacement l'angiogenèse et la croissance tumorale.
- GN10540Fumalic acidCAS: 1135-24-6Purity: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73852 | Infigratinib-Boc | 2504949-83-9 | >98.00% | |
Infigratinib-Boc est un dérivé de l’infigratinib contenant un groupe Boc (t-Butyloxy carbonyl). | ||||
| GC73947 | CEP-11981 | 856691-93-5 | >99.00% | |
CEP-11981 (esk981; bol 303213x) est un inhibiteur de tyrosine kinase (TKI) actif par voie orale qui peut cibler tie2, vegfr1 - 3 et fgfr1 avec des effets antitumoraux et antiangiogéniques potentiels. | ||||
| GC74046 | BR-cpd7 | - | >98.00% | |
BR-cpd7 est un dégradeur PROTAC pour le récepteur FGFR1/2 du facteur de croissance des fibroblastes avec DC50 de 10 nM. | ||||
| GC74365 | VSPPLTLGQLLS | 1206896-24-3 | >98.00% | |
VSPPLTLGQLLS est un petit inhibiteur du peptide fgfr3, le Peptide P3, qui inhibe la phosphorylation du fgfr3. | ||||
| GC79483 | MD-3-A45 | 2314337-87-4 | >98.00% | |
MD-3-A45 is an inhibitor of fibroblast growth factor 23 ( FGF-23 ). | ||||
| GC81314 | OM-RCA-01 | - | >99.00% | |
OM-RCA-01 is an anti- FGFR1 monoclonal antibody with a K d of 1.59 nM for human FGFR1. | ||||
| GC81319 | 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose | 150302-84-4 | >98% | |
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81325 | VEGFR2-IN-84 | 861877-12-5 | >98% | |
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold. | ||||
| GC81329 | TCB-32 hydrochloride | 169764-95-8 | >97.50% | |
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM. | ||||
| GC91419 | CYY292 | 2644673-04-9 | >98.00% | |
CYY292 est un inhibiteur de PDGFRα, PDGFRβ, FGFR1, -2 et -3 (IC50 = 5,35, 4,6, 28, 28 et 78 nM respectivement). | ||||
| GN10527 | Formononetin | 485-72-3 | >99.50% | |
Formononetin est un puissant inhibiteur de FGFR2, sa valeur d'IC50 est 4,3μM. Formononetin inhibe efficacement l'angiogenèse et la croissance tumorale. | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||