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1-Linoleoyl Glycerol (Synonyms: 1LG)

Catalog No.GC35065 Copy One-Click Copy Product Info

1-Linoleoyl Glycerol is a fatty acid glycerol.

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1-Linoleoyl Glycerol Chemical Structure

Cas No.: 2277-28-3

Size Price Stock Qty
10mM (in 1mL DMSO)
$89.00
In stock
100mg
$81.00
In stock
500mg
$162.00
In stock

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Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of 1-Linoleoyl Glycerol

1-Linoleoyl Glycerol is a fatty acid glycerol that has been isolated from S. chinensis roots. The (R)-1-Linoleoyl Glycerol and (S)-1-Linoleoyl Glycerol exhibit Lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitory activities with IC50 values of 45.0 and 52.0 μM, respectively[1].

[1]. Lee WS, et al. Lp-PLA2 inhibitory activities of fatty acid glycerols isolated from Saururus chinensis roots. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3573-5.

Chemical Properties of 1-Linoleoyl Glycerol

Cas No. 2277-28-3 SDF
Synonyms 1LG
Canonical SMILES CCCCC/C=C\C/C=C\CCCCCCCC(OCC(O)CO)=O
Formula C21H38O4 M.Wt 354.52
Solubility DMSO: ≥ 100 mg/mL (282.07 mM); Ethanol: 100 mg/mL (282.07 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 1-Linoleoyl Glycerol

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.8207 mL 14.1036 mL 28.2072 mL
5 mM 564.1 μL 2.8207 mL 5.6414 mL
10 mM 282.1 μL 1.4104 mL 2.8207 mL
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In vivo Formulation Calculator (Clear solution) of 1-Linoleoyl Glycerol

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Reviews

Review for 1-Linoleoyl Glycerol

Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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