GLPBio

DDX3-IN-1

Catalog No.: GC35823Purity:>99.50%
DDX3-IN-1 (Compound 16f) is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50s of 50 and 36 μM for HIV and HCV, respectively.

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DDX3-IN-1
Cas No.: 1919828-83-3
10mM (in 1mL DMSO)In Stock
$357.00
1
5mgIn Stock
$324.00
1
10mgIn Stock
$510.00
1
50mgIn Stock
$1,530.00
1
100mgIn Stock
$2,457.00
1

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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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Description

DDX3-IN-1 (Compound 16f) is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50s of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity[1].

[1]. Brai A, et al. Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents. Proc Natl Acad Sci U S A. 2016 May 10;113(19):5388-93.

Product Documents

Purity:>99.50%Appearance:A solid

Chemical Properties

CAS No.
1919828-83-3
SMILES
O=C(NC1=CC=C(N2N=NC(C)=C2)C=C1)NC3=CC=CC=C3C
Molecular Formula
C17H17N5O
Molecular Weight
307.35
Solubility
DMSO: 125 mg/mL (406.70 mM); Water: < 0.1 mg/mL (insoluble)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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