GLPBio

Eprobemide (LIS 630)

Catalog No.: GC30963Purity:>99.50%
COASDSData Sheet
Eprobemide (LIS 630) is a non-competitive reversible inhibitor of monoamine oxidase A.

Products are for research use only. Not for human use. We do not sell to patients.

Eprobemide (LIS 630)
Cas No.: 87940-60-1
10mM (in 1mL DMSO)In Stock
$52.00
1
1mgIn Stock
$16.00
1
5mgIn Stock
$39.00
1
10mgIn Stock
$56.00
1
25mgIn Stock
$112.00
1
50mgIn Stock
$156.00
1
100mgIn Stock
$240.00
1
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Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A.

Eprobemide is a pharmaceutical drug that is used as an antidepressant. Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination[1][2].

[1]. Gol'dina OA, et al. The action of befol and its derivatives on monoamine oxidase of different origins. Biull Eksp Biol Med. 1991 Mar;111(3):279-80. [2]. Donskaya, et al. Antidepressant Befol Synthesized Via Interaction of 4-Chloro-N-(3-chloropropyl)benzamide with Morpholine. Pharmaceutical Chemistry Journal, 2004 Jun; 38(7): 381-384.

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
87940-60-1
SMILES
O=C(NCCCN1CCOCC1)C2=CC=C(Cl)C=C2
Molecular Formula
C14H19ClN2O2
Molecular Weight
282.77
Solubility
DMSO : ≥ 125 mg/mL (442.06 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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