GLPBio

Eg5 Inhibitor V, trans-24

Catalog No.: GC35964Purity:>98%
COASDSData Sheet
Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer.

Products are for research use only. Not for human use. We do not sell to patients.

Eg5 Inhibitor V, trans-24
Cas No.: 869304-55-2
1mgIn Stock
$167.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    31, 1291–1307 (2021)

Description

Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer. Eg5|0.65 μM (IC50)

Eg5 Inhibitor V, trans-24 is a potent and specific Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer[1].

[1]. Sunder-Plassmann N, et al. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorg Med Chem. 2005 Nov 15;13(22):6094-111.

Chemical Properties

CAS No.
869304-55-2
SMILES
O=C([C@]1([H])CC2=C([C@@H](C3=CC=CC(O)=C3)N14)NC5=C2C=CC=C5)N(CC6=CC=CC=C6)C4=O
Molecular Formula
C26H21N3O3
Molecular Weight
423.46
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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