Kinesin
Kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells.
Products Related to Kinesin(29)
- GC13394Ispinesib (SB-715992)CAS: 336113-53-2Purity: >98.00%
Ispinesib (SB-715992) is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM.
- GC30393Litronesib Racemate (LY-2523355 Racemate)CAS: 546111-97-1Purity: >99.00%
Litronesib Racemate (LY-2523355 Racemate) (LY2523355 Racemate) is the racemate of litronesib.
- GC31803Litronesib (LY-2523355)CAS: 910634-41-2Purity: >98.50%
Litronesib (LY-2523355) (LY2523355) is a selective mitosis-specific kinesin Eg5 inhibitor, with antitumor activity.
- GC35964Eg5 Inhibitor V, trans-24CAS: 869304-55-2Purity: >98%
Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer.
- GC60891GW406108XCAS: 1644443-92-4Purity: >98.00%
GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC16603 | Kif15-IN-1 | 672926-32-8 | >99.50% | |
potent Kif15 kinesin inhibitor | ||||
| GC17994 | Kif15-IN-2 | 672926-33-9 | >98.50% | |
potent Kif15 kinesin inhibitor | ||||
| GC18165 | EMD534085 | 858668-07-2 | >99.00% | |
Inhibitor of the mitotic kinesin-5 | ||||
| GC10681 | Eg5-I | 1338701-15-7 | >98% | |
potent inhibitor of Eg5 | ||||
| GC11252 | CW069 | 1594094-64-0 | >99.50% | |
allosteric inhibitor of HSET, selective | ||||
| GC11656 | ARRY 520 trifluoroacetate | 885060-09-3 | >99.50% | |
A potent Eg5 inhibitor | ||||
| GC12788 | Paprotrain | 57046-73-8 | >99.50% | |
mitotic kinesin-like protein 2 (MKLP-2) inhibitor | ||||
| GC13282 | ARRY-520 R enantiomer | 885060-08-2 | >98.50% | |
| GC13394 | Ispinesib (SB-715992) | 336113-53-2 | >98.00% | |
Ispinesib (SB-715992) is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM. | ||||
| GC14600 | SB743921 | 940929-33-9 | >98.00% | |
SB743921 is a potent inhibitor of the mitotic kinesin KSP (Eg5), with a Ki of 0.1 nM. | ||||
| GC14929 | Monastrol | 254753-54-3;329689-23-8 | >99.50% | |
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC 50 value of 14μM. | ||||
| GC15659 | GSK-923295 | 1088965-37-0 | >98.00% | |
An inhibitor of CENP-E | ||||
| GC16167 | K 858 | 72926-24-0 | >99.50% | |
K858 Racemic is an ATP-uncompetitive inhibitor of kinesin Eg5 with an IC50 of 1.3 μM. | ||||
| GC16472 | ARQ 621 | 1095253-39-6 | >98% | |
Eg5 inhibitor | ||||
| GC18956 | AZ82 | 1449578-65-7 | >99.00% | |
AZ82 is a small molecule inhibitor of KIFC1/HSET, a kinesin-14 family protein that is important for assembling bipolar spindles in cancer cells containing supernumerary centrosomes. | ||||
| GC30393 | Litronesib Racemate (LY-2523355 Racemate) | 546111-97-1 | >99.00% | |
Litronesib Racemate (LY-2523355 Racemate) (LY2523355 Racemate) is the racemate of litronesib. | ||||
| GC31803 | Litronesib (LY-2523355) | 910634-41-2 | >98.50% | |
Litronesib (LY-2523355) (LY2523355) is a selective mitosis-specific kinesin Eg5 inhibitor, with antitumor activity. | ||||
| GC32969 | Dimethylenastron | 863774-58-7 | >98.00% | |
An inhibitor of EG5 | ||||
| GC34297 | PF-2771 | 2070009-55-9 | >99.50% | |
PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor, inhibiting CENP-E motor activity with an IC50 of 16.1 nM; PF-2771 is used as an anticancer agent. | ||||
| GC35964 | Eg5 Inhibitor V, trans-24 | 869304-55-2 | >98% | |
Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer. | ||||
| GC48901 | BRD9876 | 32703-82-5 | >98.00% | |
An Eg5 inhibitor | ||||
| GC60891 | GW406108X | 1644443-92-4 | >98.00% | |
GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK. | ||||
| GC72926 | PVZB1194 | 1141768-04-8 | >99.00% | |
PVZB1194 is a biphenyl-type inhibitor of Kinesin spindle protein Eg5 or KIF11. | ||||
| GC73016 | AZD4877 | 758722-49-5 | >98.00% | |
AZD4877 is another isostere to Ispinesib and also a kinesin spindle protein (Eg5) inhibitor with IC50 of 2 nM. | ||||
