GLPBio

EMD638683 R-Form

Catalog No.: GC35977Purity:>99.50%
EMD638683 R-Form is the R-form of EMD638683.

Products are for research use only. Not for human use. We do not sell to patients.


EMD638683 R-Form
Cas No.: 1184940-47-3
10mM (in 1mL DMSO)In Stock
$313.00
1
5mgIn Stock
$284.00
1
10mgIn Stock
$426.00
1
50mgIn Stock
$949.00
1
100mgIn Stock
$1,517.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. SGK1[1]

[1]. Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28(1):137-46.

Product Documents

Purity:>99.50%Appearance:A solid

Chemical Properties

CAS No.
1184940-47-3
SMILES
CC1=C(CC)C(C(NNC([C@H](O)C2=CC(F)=CC(F)=C2)=O)=O)=CC=C1O
Molecular Formula
C18H18F2N2O4
Molecular Weight
364.34
Solubility
DMSO: 180 mg/mL (494.04 mM and warming)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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