REV7/REV3L-IN-1 |
| Catalog No.GC37520 |
REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1979192-13-6
Sample solution is provided at 25 µL, 10mM.
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REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM, which directly binds to REV7 in nuclear magnetic resonance analyses, and inhibits the reactivation of a reporter plasmid containing an interstrand crosslink (ICL) in between the promoter and reporter regions[1]. IC50: 78 μM (REV7/REV3L interaction)[1]
[1]. Actis ML, et al. Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction. Bioorg Med Chem. 2016 Sep 15;24(18):4339-4346.
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