STAT3-IN-3

Name: STAT3-IN-3
Brand: GlpBio
SKU: GC37689
Availability: InStock

Catalog No.: GC37689Purity:>98.00%

STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3), with anti-proliferative activity. STAT3-IN-3 induces apoptosis in breast cancer cells. STAT3-IN-3 acts as a promising mitochondria-targeting STAT3 inhibitor for cancer research.

Products are for research use only. Not for human use. We do not sell to patients.

Cas No.: 2361304-26-7

1mgIn Stock

$143.00

5mgIn Stock

$315.00

10mgIn Stock

$495.00

Pack Size	Price	Availability	Quantity
1mg	$143.00	In Stock	1
5mg	$315.00	In Stock	1
10mg	$495.00	In Stock	1

Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.

Nature
641, 529–536 (2025)
Nature
628, 630–638 (2024)
Nature
632, 686–694 (2024)
Nature
618, 1017–1023 (2023)
Nature
610, 366–372 (2022)
Cell
187(9):2288-2304 (2024)
Cell
183(7):1867-1883 (2020)
Science
388(6745) (2025)
Science
387(6739) (2025)
Science
387(6734) (2025)
Cell Research
35, 97–116 (2025)
Cell Research
34, 683–706 (2024)
Cell Research
33, 273–287 (2023)
Cell Research
33, 546–561 (2023)
Cell Research
33, 904–922 (2023)
Cell Research
31, 1291–1307 (2021)

Description

STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3)[1]. STAT3

[1]. Cai G, et al. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors. Eur J Med Chem. 2019 Jul 15;174:236-251.

Product Documents

Batch:Purity:>98.00%Appearance:A solid

COA SDS Data Sheet

Chemical Properties

CAS No.

2361304-26-7

SMILES

BrC1=C2C(S(C(C(N3CCN(C(C4=CC5=CC=C(N(CC)CC)C=C5OC4=O)=O)CC3)=O)=C2)(=O)=O)=CC=C1

Molecular Formula

C₂₇H₂₆BrN₃O₆S

Molecular Weight

600.48

Solubility

DMSO: 5 mg/mL (8.33 mM)

Storage

Store at -20°C

General tips

Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.

Shipping Condition

Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

Mass

Volume

Concentration

Molecular Weight

g/mol

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