GLPBio

L-Moses (hydrochloride)

Catalog No.: GC45503Purity:>98.00%Synonyms: L-45
COASDSData Sheet
 

Products are for research use only. Not for human use. We do not sell to patients.

L-Moses (hydrochloride)
1mgIn Stock
$57.00
1
5mgIn Stock
$248.00
1
10mgIn Stock
$436.00
1
25mgIn Stock
$952.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

1 publicationsPublications from researchers using this product

Description

L-Moses is an inhibitor of the p300/CBP-associated factor (PCAF) bromodomain (Kd = 126 nM).1 It is selective for PCAF over GCN5 (Kd = 600 nM) and >4,500-fold selective for PCAF over BRD4. L-Moses displaces the PCAF bromodomain from histone H3.3 in a nanoBRET target engagement assay when used at a concentration of 5 μM.

References
1. Moustakim, M., Clark, P.G.K., Trulli, L., et al. Discovery of a PCAF Bromodomain Chemical Probe. Angew Chem. Int. Ed. Engl. 56(3), 827-831 (2017).

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Synonyms
L-45
SMILES
CN(C)[C@@H](C1=CC=CC=C1)[C@H](C)NC(C2=CC=CC=C23)=NN4C3=NN=C4C.Cl.Cl
Molecular Formula
C21H24N6.2HCl
Molecular Weight
433.4
Solubility
DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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