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L-Moses (hydrochloride) (Synonyms: L-45)

Catalog No.GC45503

 

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L-Moses (hydrochloride) Chemical Structure

Size Price Stock Qty
1mg
$49.00
In stock
5mg
$225.00
In stock
10mg
$398.00
In stock
25mg
$870.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

L-Moses is an inhibitor of the p300/CBP-associated factor (PCAF) bromodomain (Kd = 126 nM).1 It is selective for PCAF over GCN5 (Kd = 600 nM) and >4,500-fold selective for PCAF over BRD4. L-Moses displaces the PCAF bromodomain from histone H3.3 in a nanoBRET target engagement assay when used at a concentration of 5 μM.

References
1. Moustakim, M., Clark, P.G.K., Trulli, L., et al. Discovery of a PCAF Bromodomain Chemical Probe. Angew Chem. Int. Ed. Engl. 56(3), 827-831 (2017).

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Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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