GHK is a peptide released during extracellular matrix (ECM) protein degradation following tissue injury. It binds to copper to form GHK-Cu, a complex with diverse biological activities, including roles in tissue remodeling and wound healing, hair growth, and suppression of inflammation. GHK (1 µM) increases keratinocyte proliferation in vitro, as well as the number of cells positive for the keratinocyte stem cell marker p63 and the protein levels of integrin α6 and β1 in a skin equivalent model. It also reduces infiltration of inflammatory cells and decreases TNF-α and IL-6 protein levels in bronchoalveolar lavage fluid (BALF) in a mouse model of pulmonary fibrosis induced by bleomycin .
GHK
Catalog No.: GC43751Purity:>98.00%Synonyms: Gly-His-Lys, NSC 379527
GHK is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 49557-75-7
1mgIn Stock
$25.00
1
5mgIn Stock
$88.00
1
10mgIn Stock
$138.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $25.00 | In Stock | 1 | |
| 5mg | $88.00 | In Stock | 1 | |
| 10mg | $138.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
49557-75-7
Synonyms
Gly-His-Lys, NSC 379527
SMILES
O=C(N[C@H](C(O)=O)CCCCN)[C@@H](NC(CN)=O)CC1=CN=CN1
Molecular Formula
C14H24N6O4
Molecular Weight
340.4
Solubility
DMSO: 2.5mg/mL,PBS (pH 7.2): 10mg/mL
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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