GLPBio

GlyT

GlyT1 (glycine transporter, SLC6A9) is a member of Na+ and Cl(-)- dependent neurotransmitter transporter proteins. It regulates the glycine concentration in NMDA receptor-mediate neurotransmission.

Products Related to GlyT(19)

  • GC11195 structure
    GC11195Sarcosine
    CAS: 107-97-1
    Purity: >98.00%

    Endogenous inhibitor of GlyT1

  • GC11341 structure
    GC11341LY 2365109 hydrochloride
    CAS: 868265-28-5
    Purity: >99.00%

    glycine transporter 1 (GlyT1) inhibitor

  • GC12032 structure
    GC12032NFPS
    CAS: 405225-21-0
    Purity: >98%

    NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively.

  • GC12436 structure
    GC12436Org 25543 hydrochloride
    CAS: 495076-64-7
    Purity: >98%

    GlyT2 inhibitor

  • GC15467 structure
    GC15467ALX 5407 hydrochloride
    CAS: 200006-08-2
    Purity: >98%

    GlyT1 inhibitor,selective non-transportable

  • GC16402 structure
    GC16402Org 24598 lithium salt
    CAS: 722456-08-8
    Purity: >98%

    glial glycine transporter (GlyT1) inhibitor

  • GC10206 structure
    GC10206Bitopertin
    CAS: 845614-11-1
    Purity: >99.50%

    An inhibitor of GlyT1

  • GC31115 structure
    GC31115Tilapertin (AMG747)
    CAS: 1000690-85-6
    Purity: >98%

    Tilapertin (AMG747) is an oral inhibitor of glycine transporter type-1 (GlyT1).

  • GC35527 structure
    GC35527Bitopertin R enantiomer
    CAS: 845614-12-2
    Purity: >98%

    Bitopertin R enantiomer (RG1678 R enantiomer; RO4917838 R enantiomer) is the R-enantiomer of Bitopertin.

  • GC38888 structure
    GC38888ASP2535
    CAS: 374886-51-8
    Purity: >99.50%

    ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.

  • GC44951 structure
    GC44951Stearoyl-L-carnitine (chloride)
    CAS: 32350-57-5
    Purity: >95.00%

    Stearoyl-L-carnitine is a naturally occurring long-chain acylcarnitine.

  • GC50059 structure
    GC50059Org 24598
    CAS: 372198-97-5
    Purity: >98%

    Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo

  • GC60284 structure
    GC60284PF-03463275
    CAS: 1173239-39-8
    Purity: >99.50%

    PF-03463275 is a centrally penetrant, orally available, selective, and competitive GlyT1 (glycine transporter-1) reversible inhibitor, with a Ki of 11.6 nM.

  • GC63014 structure
    GC63014Iclepertin
    CAS: 1421936-85-7
    Purity: >98.00%

    Iclepertin is a selective glycine transporter 1 (GlyT1) inhibitor that functions by inhibiting GlyT1, thereby modulating intracellular glycine concentration.

  • GC64690 structure
    GC64690Opiranserin hydrochloride
    CAS: 1440796-75-7
    Purity: >99.00%

    Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively.

  • GC65319 structure
    GC65319GlyT1 Inhibitor 1
    CAS: 1820934-93-7
    Purity: >98.00%

    GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1.

  • GC67871 structure
    GC67871SSR504734
    CAS: 615571-23-8
    Purity: >98%
  • GC70319 structure
    GC70319ALX-1393 TFA
    Purity: >99.00%

    ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model.

  • GC79505 structure
    GC79505RPI-GLYT2-82
    Purity: >99.00%

    RPI-GLYT2-82 is a reversible, blood-brain barrier-permeable allosteric inhibitor of GlyT2 with an IC 50 value of 554 nM.