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GPLGVRGC

Catalog No.GC81555 Copy One-Click Copy Product Info

GPLGVRG C is a cysteine-tagged variant of GPLGVRG.

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GPLGVRGC Chemical Structure

Cas No.: 1257658-47-1

Size Price Stock Qty
5mg
$73.00
In stock
10mg
$115.00
In stock
25mg
$214.00
In stock
50mg
$342.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of GPLGVRGC

GPLGVRG C is a cysteine-tagged variant of GPLGVRG. GPLGVRG C is hydrolyzable by MMP13. GPLGVRG C mediates the disassembly of micelle-exosome systems, enhances chondrocyte endocytosis, and promotes responsive system uptake. GPLGVRG C confers targeted delivery and responsive release properties to micelle-exosome systems. GPLGVRG C is applicable to the research of osteoarthritis [1].

In Vitro, GPLGVRGC is specifically cleaved by active MMP13[1].

References:
[1]. Pizzorno J, et al. Health Medicine. Integr Med (Encinitas). 2022;21(6):8-14.

Chemical Properties of GPLGVRGC

Cas No. 1257658-47-1 SDF
Formula C31H55N11O9S M.Wt 757.9
Solubility DMSO: 100 mg/mL (131.94 mM; Need ultrasonic) Storage Sealed storage, away from moisture
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of GPLGVRGC

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.3194 mL 6.5972 mL 13.1944 mL
5 mM 263.9 μL 1.3194 mL 2.6389 mL
10 mM 131.9 μL 659.7 μL 1.3194 mL
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In vivo Formulation Calculator (Clear solution) of GPLGVRGC

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for GPLGVRGC

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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