GTPase
Products Related to GTPase(30)
- GC114838-CPT-2Me-cAMP, sodium saltCAS: 634207-53-7Purity: >99.50%
8-CPT-2Me-cAMP, sodium salt is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2.
- GC18260FTase Inhibitor ICAS: 149759-96-6Purity: >95.00%
FTase inhibitor I is a potent inhibitor of farnesyltransferase (FTase; IC50 = 21 nM) that is greater than 30-fold selective for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM).
- GC184268-NitroguanineCAS: 168701-80-2Purity: >98%
8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents.
- GC20107Fendiline hydrochlorideCAS: 13636-18-5Purity: >98.00%
Fendiline hydrochloride is a nonselective calcium channel blocker.
- GC39810CID44216842CAS: 1222513-26-9Purity: >99.50%
CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
- GC4045215(S)-HETE MaxSpec® StandardCAS: 54845-95-3Purity: >98.00%
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
- GC43306Compound C108CAS: 15533-09-2Purity: >98.00%
Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation.
- GC44506Oligomycin DCAS: 1404-59-7Purity: >95.00%
Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport.
- GC44763PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt)Purity: >97.00%
The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids.
- GC47601Mastoparan (trifluoroacetate salt)Purity: >95.00%
A neuropeptide with diverse biological activities
- GC49703Guanosine 5’-[γ-thio]triphosphate (lithium salt)CAS: 94825-44-2Purity: >75.00%
A hydrolysis-resistant analog of GTP
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC17852 | Gue 1654 | 397290-30-1 | >98% | |
Oxoeicosanoid receptor 1 (OXE-R) modulator | ||||
| GC11483 | 8-CPT-2Me-cAMP, sodium salt | 634207-53-7 | >99.50% | |
8-CPT-2Me-cAMP, sodium salt is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. | ||||
| GC11880 | OctMAB | 1120-02-1 | >98% | |
Dynamin inhibitor | ||||
| GC13243 | MitMAB | 1119-97-7 | >98.00% | |
MitMAB, an organic building block, is a cationic surfactant with asymmetrical structure. | ||||
| GC14179 | Dynole 34-2 | 1128165-88-7 | >98% | |
Dynamin I inhibitor | ||||
| GC15722 | HJC 0350 | 885434-70-8 | >98% | |
EPAC2 antagonist, potent and selective | ||||
| GC16199 | 8-pCPT-2-O-Me-cAMP-AM | 1152197-23-3 | >97.00% | |
Epac activator | ||||
| GC18260 | FTase Inhibitor I | 149759-96-6 | >95.00% | |
FTase inhibitor I is a potent inhibitor of farnesyltransferase (FTase; IC50 = 21 nM) that is greater than 30-fold selective for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). | ||||
| GC18426 | 8-Nitroguanine | 168701-80-2 | >98% | |
8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. | ||||
| GC18445 | N-Deacetylcolchicine | 3476-50-4 | >98% | |
An inhibitor of microtubule polymerization | ||||
| GC20107 | Fendiline hydrochloride | 13636-18-5 | >98.00% | |
Fendiline hydrochloride is a nonselective calcium channel blocker. | ||||
| GC39810 | CID44216842 | 1222513-26-9 | >99.50% | |
CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe. | ||||
| GC40452 | 15(S)-HETE MaxSpec® Standard | 54845-95-3 | >98.00% | |
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. | ||||
| GC43306 | Compound C108 | 15533-09-2 | >98.00% | |
Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. | ||||
| GC44020 | L-681,217 | - | >95.00% | |
L-681,217 is an antibiotic originally isolated from S. | ||||
| GC44506 | Oligomycin D | 1404-59-7 | >95.00% | |
Oligomycin D is a macrolide antibiotic produced by several species of Streptomyces that inhibits the mitochondrial F1FO-ATPase and is used to uncouple oxidative phosphorylation from electron transport. | ||||
| GC44763 | PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt) | - | >97.00% | |
The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. | ||||
| GC47477 | JKE-1674 | 2421119-60-8 | >98.00% | |
A GPX4 inhibitor and active metabolite of ML-210 | ||||
| GC47478 | JKE-1716 | 2421118-05-8 | >98.00% | |
A GPX4 inhibitor | ||||
| GC47601 | Mastoparan (trifluoroacetate salt) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48094 | Spiro-Oxanthromicin A | 1616622-10-6 | >95.00% | |
A polyketide | ||||
| GC49033 | Guanosine 5’-diphosphate (sodium salt hydrate) | - | >90.00% | |
A purine nucleotide | ||||
| GC49089 | FR900359 | 107530-18-7 | - | |
FR900359 is an inhibitor of G proteins Gα q , Gα 11 , and Gα 14 with IC 50 values of 13.18, 10.47, and 10nM, respectively and is isolated from the leaves of the ornamental plant Ardisia crenata | ||||
| GC49703 | Guanosine 5’-[γ-thio]triphosphate (lithium salt) | 94825-44-2 | >75.00% | |
A hydrolysis-resistant analog of GTP | ||||
