L-681,217 |
| Catalog No.GC44020 |
L-681,217 is an antibiotic originally isolated from S.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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L-681,217 is an antibiotic originally isolated from S. cattleya. It is active against Gram positive and Gram negative bacteria when used at a concentration of 255 µg/ml. L-681,217 inhibits bacterial protein synthesis at the elongation stage, completely inhibiting poly(U)-dependent poly(Phe) synthesis (EC50 = 0.4 µM) and increasing elongation factor Tu (EF-Tu)-associated GTPase activity in E. coli (EC50 = 6 µM). It does not inhibit poly(U)-dependent poly(Phe) synthesis in S. aureus (EC50 = >1,000 µM).
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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