Hexachlorophene
Catalog No.: GC10497Synonyms: Nabac, NSC 9887, NSC 49115
KCNQ1/KCNE1 potassium channel activator
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 70-30-4
500mgIn Stock
$36.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 500mg | $36.00 | In Stock | 1 |
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Citations
1 publicationsPublications from researchers using this productDescription
Hexachlorophene (Hexachlorofen) is a highly effective antibacterial agent, causes lysis of protoplasts and leakage ofintracellular contents in bacterial at high concentrations[1]. Hexachlorophene (Hexachlorofen) is also a KCNQ1/KCNE1 (a voltage-gated potassium channel) activator, with an EC50 of 4.61 μM, used in the research of severe arrhythmia[2].
References:
[1]. Lloyd WJ, et al. Cyclohexane triones, novel membrane-active antibacterial agents. Antimicrob Agents Chemother. 1988 Jun;32(6):814-8.
[2]. Zheng Y, et al. Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator which rescues LQTs mutants. PLoS One. 2012;7(12):e51820.
Product Documents
Appearance:A solid
Chemical Properties
CAS No.
70-30-4
Synonyms
Nabac, NSC 9887, NSC 49115
Chemical Name
6,6'-methylenebis(2,4,5-trichlorophenol)
SMILES
ClC1=CC(Cl)=C(Cl)C(CC2=C(Cl)C(Cl)=CC(Cl)=C2O)=C1O
Molecular Formula
C13H6Cl6O2
Molecular Weight
406.9
Solubility
≥ 40.7mg/mL in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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