Viral Diseases

UC-781 (NSC 675186) is a highly potent and selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with an IC50 value of 5 nM.

C12-TLRa is an adjuvant lipidoid.

Trifluoromethyl-tubercidin (TFMT) is a 2'-O-ribose methyltransferase 1 (MTr1) inhibitor through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication.

Famciclovir-d4 is the deuterium labeled Famciclovir.

Chloroxylenol-d6 is the deuterium labeled Chloroxylenol.

Interiorin can be isolated from Kadsura heteroclita and has moderate anti-HIV activity with an EC50 value of 1.6 lg/mL.

Gomisin M1 ((±)-Gomisin M1) is a potent anti-HIV agent with an EC50 of <0.65 μM.

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme.

Asp-Asp-Asp-Asp-Asp-Asp is a polyaspartic acid.

Zinlirvimab is a human IgG1-λ2, HIV neutralising antibody targeting to HIV-1 gp120 envelope glycoprotein (IIIB gp120 V3 loop).

Firivumab (CT-P22; CT120) is a human IgG1 monoclonal influenza A virus hemagglutinin (Anti-IAV HA) antibody.

Navivumab (CT-P23) is an influenza A virus hemagglutinin HA monoclonal antibody. neutralizes H1, H2, H5, and H9 influenza A viruses by binding to the stem fusion domain in HA2.

Diridavumab is a monoclonal anti-HA stalk antibody.

Elipovimab is a potent broadly neutralizing HIV-1 antibody for the targeted elimination of HIV-infected cellsReferences:.

BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase.

NSC260594 induces Apoptosis.

1E7-03, a low MW tetradroquinoline derivative targeting protein phosphatase-1, can inhibit HIV-1 transcription.

Trecovirsen sodium is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.

BDM-2 is an IN-LEDGF allosteric inhibitor (INLAI) of HIV-1 integrase (IN refers to integrase) (IC50=47 nM) with potent anti-Retroviral (ARV) activity.

Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor.

Antiviral agent 55 (Compound 95) is an inhibitor for human immunodeficiency virus 1 and 2 (HIV 1 and HIV 2), and exhibits antiviral activity.

Nipamovir is a nitroimidazole prodrug.

HN0037 is a selective and orally active helicase-primase inhibitor.

HIV-1 inhibitor-69 (compound Test set 1) is a HIV-1 RT inhibitor.