Iohexol-d5 |
Catalog No.GC45728 |
An internal standard for the quantification of iohexol
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 928623-33-0
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Iohexol-d5 is intended for use as an internal standard for the quantification of iohexol by GC- or LC-MS. Iohexol is a non-ionic and water-soluble contrast agent.1 It induces inhibition of electrical activity but has no excitatory effect in vitro in rat hippocampal slices and lacks any effect in vivo on ventral root flexes of feline spinal cord, indicating minimal neurotoxicity. Iohexol also induces a smaller decrease in contractile force than the ionic and high osmolarity contrast agent metrizoate in isolated rabbit hearts perfused with a 350 mg/ml solution.2 Formulations containing iohexol have been used for visualization of arteries, veins, the urinary tract, and joints using X-ray and computed tomography (CT) scan imaging techniques.
Cas No. | 928623-33-0 | SDF | |
Canonical SMILES | IC1=C(C(NCC(O)CO)=O)C(I)=C(N(C(C)=O)C([2H])([2H])C(C([2H])([2H])O)([2H])O)C(I)=C1C(NCC(O)CO)=O | ||
Formula | C19H21D5I3N3O9 | M.Wt | 826.2 |
Solubility | Methanol: slightly soluble,Water: slightly soluble | Storage | Store at -20°C |
General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. |
Prepare stock solution | |||
1 mg | 5 mg | 10 mg | |
1 mM | 1.2104 mL | 6.0518 mL | 12.1036 mL |
5 mM | 0.2421 mL | 1.2104 mL | 2.4207 mL |
10 mM | 0.121 mL | 0.6052 mL | 1.2104 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Average Rating: 5
(Based on Reviews and 8 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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