GLPBio

UCM-A86

Catalog No.: GC79509Purity:>98.50%
COASDSData Sheet
UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively.

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

UCM-A86
Cas No.: 1210899-51-6
10mM (in 1mL DMSO)In Stock
$143.00
1
5mgIn Stock
$130.00
1
10mgIn Stock
$207.00
1
25mgIn Stock
$409.00
1
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引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors with EC 50 values of 21 µM and 19 µM at GluN1/GluN3A and GluN1/GluN3B receptors, respectively. UCM-A86 selectively potentiates responses from GluN1/GluN3A/B over GluN1/GluN2A-D receptors. UCM-A86 can be used in the research of central nervous system diseases [1].

References:
[1]. Benton AJ, et al. UCM-A86 is a selective positive allosteric modulator of GluN1/GluN3 NMDA receptors. bioRxiv [Preprint]. 2025 Nov 16:2025.11.14.688378.

製品資料 (Product Documents)

Purity:>98.50%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

CAS番号
1210899-51-6
分子式
C15H13F3N4S
分子量
338.35
溶解性
DMSO: 100 mg/mL (295.55 mM; Need ultrasonic)
保存条件
Store at 4°C, stored under nitrogen
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

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