GLPBio

FLY26

Catalog No.: GC83039Purity:>99.50%
COASDSData Sheet
FLY26 is a selective partial GluN2B antagonist with an IC50 value of 0.64 μM.

제품은 연구용으로만 사용됩니다. 인체에 사용할 수 없으며 환자에게 판매하지 않습니다.

FLY26
10mM (in 1mL DMSO)In Stock
$173.00
1
5mgIn Stock
$158.00
1
10mgIn Stock
$252.00
1
25mgIn Stock
$461.00
1
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제품 설명 (Description)

FLY26 is a selective partial GluN2B antagonist with an IC50 value of 0.64 μM. FLY26 partially inhibits the GluN2B subunit of NMDA receptors, reduces calcium ion influx and reactive oxygen species (ROS) production and activates the BDNF/TrkB/CREB neuroprotective signaling pathway to alleviate neuronal excitotoxicity and mitochondrial dysfunction. FLY26 is promising for research of neurological deficits caused by cerebral ischemia-reperfusion injury [1].

References:
[1]. Fan Y, et al. A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats. Bioorg Chem. 2025 Apr 30;161:108547.

제품 문서 (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

화학적 특성 (Chemical Properties)

분자식
C22H23N5O3
분자량
405.45
용해도
DMSO: 125 mg/mL (308.30 mM; Need ultrasonic)
보관
Store at 4°C, sealed storage, away from moisture
배송 조건
평가용 샘플은 아이스팩과 함께 배송됩니다. 그 외 용량은 실온 배송되며, 요청 시 아이스팩과 함께 배송할 수 있습니다.

계산 도구 (Calculators)몰 농도 / 희석 / 분자량 / 단위 변환 / 생체 내 제형 / 용해도

g/mol

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