Viral Diseases

β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate.

δ12-Prostaglandin J2(δ12-PGJ2)는 다양한 종양 세포 성장에 항증식 효과가 있는 사이클로펜테논 프로스타글란딘(PG)입니다. δ12-프로스타글란딘 D2의 자연 발생 탈수 산물인 프로스타글란딘 J2는 카스파제 활성화를 통해 HeLa 세포에서 세포자멸사를 유도할 수 있습니다.

Pirlindole은 선택적이고 가역적인 MAO-A 억제제입니다.

2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication (IC50 = 0.3 μM in Huh-7 human hepatoma cells) that is not cytotoxic at concentrations up to 100 μM.

20-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B.

(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo.

2-아미노퓨린(염산염)은 구아노신의 형광 유사체입니다.

2-hydroxy Myristic acid is a hydroxy fatty acid that has been found in bovine, human, and horse milk, cow and buffalo cheeses, sea bass filet, seal oil, human vernix caseosa, and wool wax.

4-hydroxy Nebivolol is a major metabolite of nebivolol.

C22 Sphingomyelin is a naturally occurring form of sphingomyelin.

CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM).

D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants.

Gallotannin (탄닌산)은 다양한 식물에서 발견된 자연적 폴리페놀 합성물로 항산화, 항염증, 항혈관생성, 항바이러스 및 항종양 생물학적 활성이 있다. Gallotannin은 DNA polymerase α, β, κ의 활동을 억제하고 그 IC50 값이 각각 13, 130, 30nM이다.

Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit.

KIN1400 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity.

Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.

SD 1029는 JAK2/STAT3 억제제입니다. SD 1029는 STAT3 핵 전위를 억제합니다. SD 1029는 JAK2 인산화 억제로 인한 STAT3 활성화 억제제입니다.

Simeprevir(TMC435; TMC435350) 나트륨은 0.36nM의 Ki를 갖는 경구, 강력하고 고도로 특이적인 C형 간염 바이러스(HCV) NS3/4A 프로테아제 억제제입니다.

Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM).

Toll-Like Receptor 7 Ligand II(CL-087)는 강력한 경구 활성 TLR7 작용제입니다.

Vasoactive intestinal peptide (VIP) is a peptide that acts as a neurotransmitter and hormone.

스쿠알렌 합성효소 억제제인 YM-53601은 생체 내에서 혈장 콜레스테롤과 중성지방 수치를 감소시킵니다.

S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine.