KIN1400 |
| Catalog No.GC44005 |
KIN1400 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 446826-86-4
Sample solution is provided at 25 µL, 10mM.
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KIN1400 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces expression of the innate immune genes RIG-1, MDA5, IFIT1, IFIT2, IFITM1, OAS3, and Mx1 in THP-1 cells stimulated with phorbol 12-myristate 13-acetate . KIN1400 (20 μM) reduces West Nile and dengue viral RNA levels in HEK293 and Huh7 cells, respectively. It also inhibits hepatitis C virus (HCV) replication in a concentration-dependent manner in Huh7 cells.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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