Innate Immunity
Products for Innate Immunity
- Cat.No. 상품명 정보
- GC18602 p38 MAPK Inhibitor IV p38 MAPK 억제제 IV는 고도로 특이적인 ATP-경쟁적 p38α입니다. 0.13 및 0.55의 IC50을 갖는 MAPK 억제제 μ p38α의 경우 M; 및 p38β MAPK.
- GC52342 P4pal10 (trifluoroacetate salt) A PAR4 and FPR2 antagonist and an FFAR2 agonist
- GC44540 PAF C-16 Carboxylic Acid PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways.
- GC47855 PAF C-16-d4 An internal standard for the quantification of PAF C16
- GC44541 PAF C-18 PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways.
- GC41450 PAF C-18:1 PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response.
- GC49024 Palmitic Acid MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49023 Palmitic Acid-d9 MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49061 Pam2CSK4 (trifluoroacetate salt) A bacterial lipopeptide and TLR2 agonist
- GC49422 PAR2 (1-6) amide (human) (trifluoroacetate salt) A peptide agonist of PAR2
- GC44579 PCTR1 PCTR1은 강력한 단핵구/대식세포 작용제로서 박테리아 감염 동안 주요 항염증 및 프로 해결 과정을 조절합니다.
- GC44580 PCTR2 Protein conjugates in tissue regeneration 2 (PCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid.
- GC44581 PCTR3 Protein conjugates in tissue regeneration 3 (PCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid.
- GC47931 PDE4B Inhibitor A PDE4B inhibitor
- GC44590 Pellitorine Pellitorine은 Piper nigrum의 뿌리에서 분리된 화합물입니다. Pellitorine은 HL60 및 MCT-7 세포주에 대해 강력한 세포독성 활성을 나타냅니다. Pellitorine은 암 질환 연구의 잠재력을 가지고 있습니다.
- GC52127 Pexiganan (acetate)
- GC44633 Phosphatidylserines (bovine) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.
- GC18522 Phosphatidylserines (sodium salt) Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina.
- GC49265 PKI (14-22) amide (myristoylated) (trifluoroacetate salt) A PKA inhibitor
- GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor
- GC47964 pNPS-DHA An anti-allergic DHEA derivative
- GC52270 Pranoprofen-13C-d3 An internal standard for the quantification of pranoprofen
- GC48501 Preterramide C Preterramide C는 곰팡이 대사 산물입니다.
- GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.
- GC47988 Prostaglandin D2-d4 An internal standard for the quantification of prostaglandin D2
- GC40981 Protectin D1 프로텍틴 D1, 신경 세포에 의해 생성될 때 신경 프로텍틴 D1은 도코사헥사엔산에서 생성되는 새로운 생리 활성 제품 계열의 구성원입니다.
- GC48993 Protectin D1-d5 An internal standard for the quantification of protectin D1
- GC44794 Pyrrophenone 피로페논은 IC50 값이 4.2nM인 강력하고 특이적인 세포질 포스포리파제 A2α(cPLA2α) 억제제입니다.
- GC40004 Quinolactacin A 퀴노락타신 A는 TNF 생성 억제제입니다.
- GC44802 R-8507 R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNF-αRI).
- GC48461 rac-trans-4-hydroxy Glyburide An active metabolite of glyburide
- GC48035 RCTR1 A specialized pro-resolving mediator
- GC41231 Resolvin D2 methyl ester Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.
- GC49279 Resolvin D2 n-3 DPA A specialized pro-resolving mediator
- GC48042 Resolvin D2-d5 An internal standard for the quantification of RvD2
- GC41232 Resolvin D3 methyl ester Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties.
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GC44818
Resolvin D4
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid.
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GC40982
Resolvin D5
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.
- GC48972 Resolvin E2 A specialized pro-resolving mediator
- GC48045 Resolvin E4 A specialized pro-resolving mediator
- GC44820 Resveratrol-3-O-Sulfate (sodium salt) Resveratrol-3-O-sulfate(나트륨)는 Resveratrol의 대사 산물입니다.
- GC41189 Ricinelaidic Acid Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 μM in porcine neutrophil membranes).
- GC44839 Ridaifen-B An analog of tamoxifen
- GC48048 Rifampicin-d3 An internal standard for the quantification of rifampicin
- GC44851 Rosiglitazone (potassium salt) Rosiglitazone(BRL 49653) 칼륨은 경구 활성 선택적 PPARγ입니다. 작용제(EC50: 60nM, Kd: 40nM).
- GC48059 Rosiglitazone-d3 An internal standard for the quantification of rosiglitazone
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GC41626
Sappanone A
사파논 A는 강한 항산화 및 항염증 활성을 가진 호모이소플라바논입니다.
- GC46221 Seselin An angular pyranocoumarin with diverse biological activities
- GC18821 SGA360 SGA360은 AHR이 동족 반응 요소(부분 길항제)에 결합할 필요가 없는 기전을 통해 AHR 의존적 방식으로 염증성 SAA1 신호 전달을 억제합니다.
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GC49333
SH-42
DHCR24의 억제제
- GC49002 Sinigrin (hydrate) 시니그린(수화물)은 십자화과과 식물에 존재하는 천연 지방족 글루코시놀레이트입니다.
- GC49049 SMU127 An agonist of TLR1/2
- GC49400 SN-011 SN-011은 STING 신호전달에 대한 IC50이 76nM인 강력하고 선택적인 마우스 및 인간 STING 억제제입니다.
- GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.
- GC44919 SP 600125, negative control SP 600125 is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.
- GC44930 Sphingosine (d14:1) 스핑고신(d14:1)(테트라데카스핑-4-에닌)은 스핑고리피드로 강력한 PKC(단백질 키나제 C) 억제제입니다. 스핑고신(d14:1)은 sn-1,2-디아실글리세롤(DAG)/포르볼 에스테르와의 상호작용을 방지합니다.
- GC48098 SR 12343 An IKKβ NBD mimetic
- GC48099 SR 12460 An IKKβ NBD mimetic
- GC45567 SR 1903
- GC61293 SR-717 SR-717은 ISG-THP1(WT) 및 ISG-THP1 cGAS KO(cGAS KO) 세포주에서 EC50이 각각 2.1μM 및 2.2μM인 비뉴클레오티드 STING 작용제입니다.
- GC45831 SRI-011381 SRI-011381은 경구 활성 TGF-β 신호 작용제로 신경 보호 효과를 나타냅니다.
- GC40922 SRS11-92 Ferrostatin-1(Fer-1) 유사체인 SRS11-92는 강력한 ferroptosis 억제제입니다.
- GC44948 StA-IFN-1 StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1, which specifically inhibits the IKKβ component of the IFN induction pathway.
- GC49844 Stercobilin (hydrochloride) A fecal pigment and metabolite of bilirubin
- GC48109 STING Agonist 12b A STING agonist
- GC48110 STING Agonist 1a STING 작용제 1a(1a)는 인터페론 유전자(STING) 작용제의 특정 자극제입니다.
- GC45570 STING Agonist C11
- GC46227 STING18 A competitive STING ligand
- GC44956 Streptochlorin Streptochlorin is a bacterial metabolite originally isolated from Streptomyces sp.
- GC52496 Sulfatide (bovine) (sodium salt) A mixture of isolated bovine sulfatides
- GC44968 Sulfatides (bovine) (sodium salt) Sulfatides are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system.
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GC18453
Sulochrin
Sulochrin은 A에 의해 생산되는 곰팡이 대사 생성물입니다.
- GC48764 Sydowinin B A xanthone polyketide with immunosuppressant activity
- GC49047 T-5342126 A TLR4 antagonist
- GC48447 TAS 205 An inhibitor of H-PGDS
- GC44999 Tauro-α-muricholic Acid (sodium salt) Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid.
- GC45004 TC 14012 (trifluoroacetate salt) C-X-C chemokine receptor type 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 which is designated as chemokine ligand 12 (CXCL12).
- GC49105 Tebipenem (hydrate) A carbenapenem antibiotic
- GC45012 Tenofovir diphosphate (sodium salt) Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM).
- GC49386 Tepoxalin 테폭살린은 COX와 5-LO(5-lipoxygenase)의 이중 억제제로서 강력한 항염증 활성과 유리한 위장 프로필을 가지고 있습니다.
- GC40627 tetranor-Misoprostol tetranor-Misoprostol is a metabolite of misoprostol.
- GC19001 Tetromycin B Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively.
- GC45030 TG6-129 TG6-129는 EP2 수용체의 선택적 길항제입니다.
- GC48163 Theophylline-d6 Theophylline-d6(1,3-Dimethylxanthine-d6)은 Theophylline이라고 표시된 중수소입니다. 테오필린은 비선택적 포스포디에스테라제(PDE) 억제제, 아데노신 수용체 차단제 및 히스톤 데아세틸라제(HDAC) 활성제입니다.
- GC49503 Thujopsene A sesquiterpene with diverse biological activities
- GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide
- GC49062 Tiopronin-d3 티오프로닌-d3은 티오프로닌으로 표시된 중수소입니다.
- GC45057 TIQ-A TIQ-A는 TNKS2에 대해 IC50이 24nM인 강력한 TNKS(폴리-ART, PARP) 억제제입니다.
- GC45965 Tolfenamic Acid-d4 An internal standard for the quantification of tolfenamic acid
- GC45063 Toll-Like Receptor 7 Ligand II Toll-Like Receptor 7 Ligand II(CL-087)는 강력한 경구 활성 TLR7 작용제입니다.
- GC49150 Tpl2 Kinase Inhibitor (hydrochloride) A Tpl2 inhibitor
- GC48202 Treprostinil (diethanolamine salt) 트레프로스티닐(UT-15C) 디에탄올아민은 EP2, DP1, IP, EP1, FP4, EP3에 대해 각각 3.6, 4.4, 32.1, 212, 826, 2505 및 4680nM의 Ki 값을 갖는 강력한 EP2, DP1 및 IP 작용제입니다. .
- GC49685 Trifluoroacetyl Tripeptide-2 (acetate) A peptide inhibitor of pancreatic and neutrophil elastases
- GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline
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GC41638
TSI-01
혈소판 활성화 인자(PAF)는 외부 자극에 대한 반응으로 라이소-PAF 아세틸전이효소(lyso-PAFAT)에 의해 신속하게 합성되는 염증 유도 인지질 매개체입니다.
- GC52412 TT-232 (trifluoroacetate salt) A synthetic peptide derivative of somatostatin
- GC49099 Tuftsin (human) (trifluoroacetate salt) A phagocytosis-stimulating peptide
- GC49835 Tumulosic Acid 트리테르페노이드인 투물로식산은 KLK5 프로테아제 활성을 억제합니다(IC50= 14.84 μM).
- GC48987 UDP (sodium salt hydrate) An agonist of P2Y6
- GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide