5(S),12(S)-DiHETE |
| Catalog No.GC41126 |
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 79056-01-2
Sample solution is provided at 25 µL, 10mM.
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5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid . It is synthesized by glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNLs) incubated with AA. 5(S),12(S)-DiHETE can be produced by successive oxygenation of AA by 5-lipoxygenase (5-LO) in platelets and 12-LO in leukocytes. It can also be synthesized from 12(S)-HETE by 5-LO, in the presence of 5-LO activating protein (FLAP), activated with calcium ionophore. 5(S),12(S)-DiHETE is an epimer of leukotriene B4 that is weakly chemotactic for PMNL.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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