15-deoxy-δ12,14-Prostaglandin D2 (Synonyms: 15deoxyΔ12,14PGD2) |
| Catalog No.GC41102 |
15-deoxy-δ12,14-PGD2 is a synthetic analog of PGD2 and a potential precursor to the PPARγ ligand 15-deoxy-δ12,14-PGJ2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 85235-11-6
Sample solution is provided at 25 µL, 10mM.
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15-deoxy-δ12,14-PGD2 is a synthetic analog of PGD2 and a potential precursor to the PPARγ ligand 15-deoxy-δ12,14-PGJ2. It possesses cytotoxic effects on L1210 mouse leukemia cells in vitro with an IC50 of 0.3 µg/ml. 15-deoxy-δ12,14-PGD2 is 10-fold more potent than PGD2 in this activity. However, it is a less effective inhibitor of ADP-induced platelet aggregation (IC50 = 320 ng/ml) compared to PGD2 (IC50 = 3 ng/ml).
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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