GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC44509 structure
    GC44509Omeprazole sulfide
    CAS: 73590-85-9
    Purity: >99.50%

    오메프라졸 대사산물 오메프라졸 황화물(Ufiprazole)은 양성자 펌프 억제제인 오메프라졸의 대사산물입니다.

  • GC44527 structure
    GC44527p,p'-DDE
    CAS: 72-55-9
    Purity: >99.00%

    지속성 디클로로디페닐트리클로로에탄(DDT)의 주요 대사산물인 p,p'-DDE(4,4'-DDE)는 IC50이 5μM이고 Ki가 3.5μM인 강력한 안드로겐 수용체 길항제입니다.

  • GC44554 structure
    GC44554Pantoprazole Sulfide
    CAS: 102625-64-9
    Purity: >98.00%

    Pantoprazole sulfide is a metabolite of the gastric H+/K+ ATPase pump inhibitor pantoprazole.

  • GC44555 structure
    GC44555Pantoprazole sulfone
    CAS: 127780-16-9
    Purity: >98.00%

    Pantoprazole sulfone is a metabolite of the gastric H+/K+ ATPase pump inhibitor pantoprazole.

  • GC44599 structure
    GC44599Perindoprilat
    CAS: 95153-31-4
    Purity: >95.00%

    Perindoprilat(S 9780)은 1.5~3.2nM 범위의 IC50 값을 갖는 안지오텐신 전환 효소(ACE) 억제제입니다.

  • GC44627 structure
    GC44627Phenylephrine Glucuronide
    CAS: 2021255-73-0
    Purity: >95.00%

    Phenylephrine glucuronide is a metabolite of the α1A-adrenergic receptor agonist phenylephrine .

  • GC44628 structure
    GC44628Phenylephrine-3-O-Sulfate
    CAS: 1242184-39-9
    Purity: >85.00%

    Phenylephrine-3-O-sulfate is metabolite of the α1A-adrenergic receptor agonist phenylephrine formed via sulfation.

  • GC44650 structure
    GC44650Pitavastatin lactone
    CAS: 141750-63-2
    Purity: >98.00%

    피타바스타틴 락톤은 인간에서 피타바스타틴의 주요 대사 산물입니다.

  • GC44665 structure
    GC44665PNU 142300
    CAS: 368891-69-4
    Purity: >95.00%

    PNU 142300 is an inactive metabolite of the oxazolidinone antibiotic linezolid .

  • GC44668 structure
    GC44668Posaconazole D-Glucuronide
    Purity: >80.00%

    Posaconazole D-glucuronide is a metabolite of the antifungal agent posaconazole.

  • GC44676 structure
    GC44676Pravastatin lactone
    CAS: 85956-22-5
    Purity: >98.00%

    Pravastatin lactone is a metabolite of pravastatin, a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin.

  • GC44699 structure
    GC44699Propranolol β-D-Glucuronide (sodium salt)
    Purity: >95.00%

    Propranolol β-D-glucuronide is a major metabolite of propranolol.

  • GC44799 structure
    GC44799Quinidine N-oxide
    CAS: 70116-00-6
    Purity: >95.00%

    Quinidine N-oxide is a pharmacologically inactive quinidine metabolite.

  • GC44803 structure
    GC44803rac-7-hydroxy Propranolol (hydrochloride)
    CAS: 76275-67-7
    Purity: >98.00%

    rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).

  • GC44810 structure
    GC44810Reduced Haloperidol
    CAS: 34104-67-1
    Purity: >98.00%

    Reduced haloperidol is an active metabolite of haloperidol.

  • GC44820 structure
    GC44820Resveratrol-3-O-Sulfate (sodium salt)
    CAS: 858127-11-4
    Purity: >95.00%

    Resveratrol-3-O-sulfate(나트륨)는 Resveratrol의 대사 산물입니다.

  • GC44890 structure
    GC44890Silodosin Glucuronide (sodium salt)
    CAS: 879292-24-7
    Purity: >95.00%

    Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin.

  • GC44895 structure
    GC44895Sitagliptin N-Sulfate (sodium salt)
    CAS: 2470126-25-9
    Purity: >95.00%

    Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.

  • GC44912 structure
    GC44912Solifenacin N-Glucuronide
    Purity: >85.00%

    Solifenacin N-glucuronide is a metabolite of the muscarinic receptor antagonist solifenacin formed by direct glucuronidation.

  • GC44913 structure
    GC44913Solifenacin N-oxide
    CAS: 180272-28-0
    Purity: >98.00%

    Solifenacin N-oxide is an inactive metabolite of the muscarinic receptor antagonist solifenacin.

  • GC44917 structure
    GC44917Sorafenib N-oxide
    CAS: 583840-03-3
    Purity: >98.00%

    Sorafenib N-oxide is an active metabolite of sorafenib, an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases.

  • GC45001 structure
    GC45001Tazarotenic Acid
    CAS: 118292-41-4
    Purity: >98.00%

    Tazarotenic acid는 Tazarotene의 대사 산물입니다.

  • GC45007 structure
    GC45007Telmisartan Acyl-β-D-Glucuronide
    CAS: 250780-40-6
    Purity: >95.00%

    Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan.

  • GC45012 structure
    GC45012Tenofovir diphosphate (sodium salt)
    Purity: >95.00%

    Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM).