Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(546)
- GC43493DL-Sulforaphane N-acetyl-L-cysteineCAS: 334829-66-2Purity: >98.00%
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress.
- GC43565Doxorubicinol (hydrochloride)CAS: 63950-05-0Purity: >90.00%
Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks.
- GC43646Ezetimibe Hydroxy GlucuronideCAS: 536709-33-8Purity: >95.00%
Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe .
- GC43675Florfenicol amine (hydrochloride)CAS: 108656-33-3Purity: >95.00%
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine.
- GC43697Formoterol O-β-D-GlucuronideCAS: 615551-59-2Purity: >95.00%
Formoterol O-β-D-glucuronide is a metabolite of formoterol .
- GC43743Gemfibrozil 1-O-β-GlucuronideCAS: 91683-38-4Purity: >99.5%
Gemfibrozil 1-O-β - Gemfibrozil의 대사산물인 Glucuronide는 IC50이 4.07 μ인 강력하고 경쟁력 있는 P450(CYP) 동형 CYP2C8 억제제입니다.
- GC43878Hydroxy DimetridazoleCAS: 936-05-0Purity: >98.50%
하이드록시 디메트리다졸(Hydroxy dimetridazole)은 디메트리다졸의 하이드록시 대사 산물입니다.
- GC43895Iloperidone metabolite P88CAS: 133454-55-4Purity: >99.50%
일로페리돈 대사산물 P88(P88; Hydroxy Iloperidone)은 비정형 항정신병약물인 일로페리돈의 대사산물입니다.
- GC43896Iloperidone metabolite P95CAS: 475110-48-6Purity: >98.00%
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone.
- GC44033Lansoprazole sulfoneCAS: 131926-99-3Purity: >98.00%
Lansoprazole sulfone is a phase I metabolite of lansoprazole.
- GC44246Moxifloxacin N-Sulfate (sodium salt)Purity: >95.00%
Moxifloxacin N-sulfate is a metabolite of moxifloxacin.
- GC44294N-acetyl DapsoneCAS: 565-20-8Purity: >95.00%
N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders.
- GC44299N-Acetyl-4-benzoquinone imineCAS: 50700-49-7Purity: >90.00%
N-아세틸-4-벤조퀴논 이민은 아세트아미노펜의 독성 대사 산물입니다.
- GC44304N-Acetyl-S-allyl-L-cysteineCAS: 23127-41-5Purity: >98.00%
L-Deoxyalliin, also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities.
- GC44345N-Desethyl VardenafilCAS: 448184-46-1Purity: >98.00%
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.
- GC44348N-desmethyl BendamustineCAS: 41515-13-3Purity: >95.00%
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine.
- GC44350N-Desmethyl SildenafilCAS: 139755-82-1Purity: >98.00%
N-Desmethyl Sildenafil(Desmethylsildenafil)은 Sildenafil의 주요 대사 산물입니다.
- GC44351N-Desmethyl Sildenafil (citrate)Purity: >98.00%
N-Desmethyl sildenafil is a major metabolite of sildenafil.
- GC44358Nebivolol O-β-D-GlucuronidePurity: >95.00%
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.
- GC44451Norfluoxetine (hydrochloride)CAS: 57226-68-3Purity: >98.00%
Norfluoxetine (hydrochloride)은 간에서 N-디메틸화를 통해 생성되는 플루옥세틴의 활성 대사물질로 경구 활성을 가진다.
- GC44492O-Desmethyl MetoprololCAS: 62572-94-5Purity: >99.00%
O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC43493 | DL-Sulforaphane N-acetyl-L-cysteine | 334829-66-2 | >98.00% | |
Nrf2 activation of the antioxidant response element (ARE) is central to cytoprotective gene expression against oxidative and/or electrophilic stress. | ||||
| GC43565 | Doxorubicinol (hydrochloride) | 63950-05-0 | >90.00% | |
Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. | ||||
| GC43646 | Ezetimibe Hydroxy Glucuronide | 536709-33-8 | >95.00% | |
Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe . | ||||
| GC43675 | Florfenicol amine (hydrochloride) | 108656-33-3 | >95.00% | |
Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine. | ||||
| GC43697 | Formoterol O-β-D-Glucuronide | 615551-59-2 | >95.00% | |
Formoterol O-β-D-glucuronide is a metabolite of formoterol . | ||||
| GC43743 | Gemfibrozil 1-O-β-Glucuronide | 91683-38-4 | >99.5% | |
Gemfibrozil 1-O-β - Gemfibrozil의 대사산물인 Glucuronide는 IC50이 4.07 μ인 강력하고 경쟁력 있는 P450(CYP) 동형 CYP2C8 억제제입니다. | ||||
| GC43878 | Hydroxy Dimetridazole | 936-05-0 | >98.50% | |
하이드록시 디메트리다졸(Hydroxy dimetridazole)은 디메트리다졸의 하이드록시 대사 산물입니다. | ||||
| GC43879 | Hydroxy Ebastine | 210686-41-2 | >87.00% | |
Hydroxy Ebastine is an ebastine metabolite. | ||||
| GC43881 | Hydroxy Varenicline | 357424-21-6 | >95.00% | |
A metabolite of varenicline | ||||
| GC43895 | Iloperidone metabolite P88 | 133454-55-4 | >99.50% | |
일로페리돈 대사산물 P88(P88; Hydroxy Iloperidone)은 비정형 항정신병약물인 일로페리돈의 대사산물입니다. | ||||
| GC43896 | Iloperidone metabolite P95 | 475110-48-6 | >98.00% | |
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone. | ||||
| GC44033 | Lansoprazole sulfone | 131926-99-3 | >98.00% | |
Lansoprazole sulfone is a phase I metabolite of lansoprazole. | ||||
| GC44246 | Moxifloxacin N-Sulfate (sodium salt) | - | >95.00% | |
Moxifloxacin N-sulfate is a metabolite of moxifloxacin. | ||||
| GC44294 | N-acetyl Dapsone | 565-20-8 | >95.00% | |
N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. | ||||
| GC44299 | N-Acetyl-4-benzoquinone imine | 50700-49-7 | >90.00% | |
N-아세틸-4-벤조퀴논 이민은 아세트아미노펜의 독성 대사 산물입니다. | ||||
| GC44304 | N-Acetyl-S-allyl-L-cysteine | 23127-41-5 | >98.00% | |
L-Deoxyalliin, also known as S-allyl-L-cysteine, is a water soluble organosulfur compound derived from garlic that has neuroprotective and antioxidative activities. | ||||
| GC44345 | N-Desethyl Vardenafil | 448184-46-1 | >98.00% | |
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5. | ||||
| GC44348 | N-desmethyl Bendamustine | 41515-13-3 | >95.00% | |
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine. | ||||
| GC44349 | N-desmethyl Levofloxacin | 117707-40-1 | >98.00% | |
N-데스메틸 레보플록사신은 레보플록사신의 대사 산물입니다. | ||||
| GC44350 | N-Desmethyl Sildenafil | 139755-82-1 | >98.00% | |
N-Desmethyl Sildenafil(Desmethylsildenafil)은 Sildenafil의 주요 대사 산물입니다. | ||||
| GC44351 | N-Desmethyl Sildenafil (citrate) | - | >98.00% | |
N-Desmethyl sildenafil is a major metabolite of sildenafil. | ||||
| GC44358 | Nebivolol O-β-D-Glucuronide | - | >95.00% | |
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol. | ||||
| GC44451 | Norfluoxetine (hydrochloride) | 57226-68-3 | >98.00% | |
Norfluoxetine (hydrochloride)은 간에서 N-디메틸화를 통해 생성되는 플루옥세틴의 활성 대사물질로 경구 활성을 가진다. | ||||
| GC44492 | O-Desmethyl Metoprolol | 62572-94-5 | >99.00% | |
O-Desmethyl metoprolol is the major active metabolite of the β1-adrenergic receptor blocker metoprolol. | ||||