Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(559)
- GC413995α-dihydro LevonorgestrelCAS: 78088-19-4Purity: >95.00%
5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel.
- GC414803'-hydroxy LidocaineCAS: 34604-55-2Purity: >98.00%
3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4.
- GC415653-hydroxy MedetomidineCAS: 128366-50-7Purity: >95.00%
3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine.
- GC41661(±)-4-hydroxy Propranolol β-D-GlucuronideCAS: 94731-13-2Purity: >90.00%
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.
- GC41671(±)-Equol 4'-sulfate (sodium salt)CAS: 1189685-28-6Purity: >90.00%
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
- GC41694(3S)-hydroxy QuinidineCAS: 53467-23-5Purity: >98.00%
(3S)-hydroxy Quinidine is an active quinidine metabolite.
- GC41722(R,S)-Carvedilol GlucuronideCAS: 114869-83-9Purity: >95.00%
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.
- GC41736(S)-Dibutyl 3-Hydroxybutyl PhosphateCAS: 2108602-99-7Purity: >95.00%
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP).
- GC418371,3,7-Trimethyluric AcidCAS: 5415-44-1Purity: >98.00%
1,3,7-트리메틸요르산은 카페인의 대사산물입니다. 카페인에 대한 대사 비율 1,3,7-Trimethyluric Acid는 코호트에서 CYP3A 활성의 가변성을 설명하는 바이오마커로 평가될 수 있습니다.
- GC4193715-keto-17-phenyl trinor Prostaglandin F2α ethyl amideCAS: 1163135-96-3Purity: >98.00%
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.
- GC421892-oxo ClopidogrelCAS: 109904-27-0Purity: >98.00%
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
- GC421983-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)CAS: 1346603-21-1Purity: >98.00%
An inactive metabolite of baclofen
- GC422743-hydroxy DarifenacinCAS: 206048-82-0Purity: >95.00%
3-hydroxy Darifenacin is a metabolite of darifenacin.
- GC422753-hydroxy DesloratidineCAS: 119410-08-1Purity: >98.00%
3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.
- GC423073-O-methyl-L-DOPA (hydrate)CAS: 200630-46-2Purity: >98.00%
3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase.
- GC423704-desmethoxy OmeprazoleCAS: 110374-16-8Purity: >98.00%
4-Desmethoxy Omeprazole은 Omeprazole의 활성 대사 산물입니다.
- GC424014-hydroperoxy CyclophosphamideCAS: 39800-16-3Purity: >95.00%
4-hydroperoxy Cyclophosphamide은 시클로포스파미드의 활성 메타볼라이트로 DNA를 크로스링크하고 카스파제 수용체 활성화에 독립적으로 T세포의 사멸을 유도한다. 게다가 활성산소종(ROS)의 생산을 통해 미토콘드리아 사망 경로를 활성화한다.
- GC424024-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt)Purity: >95.00%
4-hydroxy (S)-Duloxetine β-D-glucuronide is an inactive metabolite of the serotonin and norepinephrine reuptake inhibitor (S)-duloxetine.
- GC424054-hydroxy Atorvastatin (calcium salt)CAS: 265989-44-4Purity: >90.00%
4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
- GC424074-hydroxy DiclofenacCAS: 64118-84-9Purity: >97.00%
4-하이드록시 디클로페낙은 시토크롬 P450 2C9(CYP2C9)에 의한 디클로페낙의 경구 활성 대사 산물입니다.
- GC424094-hydroxy Nebivolol (hydrochloride)CAS: 2717115-85-8Purity: >98.00%
4-hydroxy Nebivolol is a major metabolite of nebivolol.
- GC424154-hydroxy ValsartanCAS: 188259-69-0Purity: >98.00%
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan.
- GC425465-hydroxy DiclofenacCAS: 69002-84-2Purity: >98.00%
5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4.
- GC425485-hydroxy Saxagliptin (hydrochloride)Purity: >95.00%
5-hydroxy Saxagliptin is a major active metabolite of saxagliptin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC41399 | 5α-dihydro Levonorgestrel | 78088-19-4 | >95.00% | |
5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel. | ||||
| GC41480 | 3'-hydroxy Lidocaine | 34604-55-2 | >98.00% | |
3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4. | ||||
| GC41565 | 3-hydroxy Medetomidine | 128366-50-7 | >95.00% | |
3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine. | ||||
| GC41661 | (±)-4-hydroxy Propranolol β-D-Glucuronide | 94731-13-2 | >90.00% | |
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol. | ||||
| GC41671 | (±)-Equol 4'-sulfate (sodium salt) | 1189685-28-6 | >90.00% | |
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol. | ||||
| GC41694 | (3S)-hydroxy Quinidine | 53467-23-5 | >98.00% | |
(3S)-hydroxy Quinidine is an active quinidine metabolite. | ||||
| GC41722 | (R,S)-Carvedilol Glucuronide | 114869-83-9 | >95.00% | |
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. | ||||
| GC41736 | (S)-Dibutyl 3-Hydroxybutyl Phosphate | 2108602-99-7 | >95.00% | |
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). | ||||
| GC41837 | 1,3,7-Trimethyluric Acid | 5415-44-1 | >98.00% | |
1,3,7-트리메틸요르산은 카페인의 대사산물입니다. 카페인에 대한 대사 비율 1,3,7-Trimethyluric Acid는 코호트에서 CYP3A 활성의 가변성을 설명하는 바이오마커로 평가될 수 있습니다. | ||||
| GC41937 | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | 1163135-96-3 | >98.00% | |
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. | ||||
| GC42189 | 2-oxo Clopidogrel | 109904-27-0 | >98.00% | |
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel. | ||||
| GC42198 | 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) | 1346603-21-1 | >98.00% | |
An inactive metabolite of baclofen | ||||
| GC42274 | 3-hydroxy Darifenacin | 206048-82-0 | >95.00% | |
3-hydroxy Darifenacin is a metabolite of darifenacin. | ||||
| GC42275 | 3-hydroxy Desloratidine | 119410-08-1 | >98.00% | |
3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor. | ||||
| GC42307 | 3-O-methyl-L-DOPA (hydrate) | 200630-46-2 | >98.00% | |
3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase. | ||||
| GC42370 | 4-desmethoxy Omeprazole | 110374-16-8 | >98.00% | |
4-Desmethoxy Omeprazole은 Omeprazole의 활성 대사 산물입니다. | ||||
| GC42401 | 4-hydroperoxy Cyclophosphamide | 39800-16-3 | >95.00% | |
4-hydroperoxy Cyclophosphamide은 시클로포스파미드의 활성 메타볼라이트로 DNA를 크로스링크하고 카스파제 수용체 활성화에 독립적으로 T세포의 사멸을 유도한다. 게다가 활성산소종(ROS)의 생산을 통해 미토콘드리아 사망 경로를 활성화한다. | ||||
| GC42402 | 4-hydroxy (S)-Duloxetine β-D-Glucuronide (sodium salt) | - | >95.00% | |
4-hydroxy (S)-Duloxetine β-D-glucuronide is an inactive metabolite of the serotonin and norepinephrine reuptake inhibitor (S)-duloxetine. | ||||
| GC42405 | 4-hydroxy Atorvastatin (calcium salt) | 265989-44-4 | >90.00% | |
4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. | ||||
| GC42407 | 4-hydroxy Diclofenac | 64118-84-9 | >97.00% | |
4-하이드록시 디클로페낙은 시토크롬 P450 2C9(CYP2C9)에 의한 디클로페낙의 경구 활성 대사 산물입니다. | ||||
| GC42409 | 4-hydroxy Nebivolol (hydrochloride) | 2717115-85-8 | >98.00% | |
4-hydroxy Nebivolol is a major metabolite of nebivolol. | ||||
| GC42415 | 4-hydroxy Valsartan | 188259-69-0 | >98.00% | |
4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan. | ||||
| GC42546 | 5-hydroxy Diclofenac | 69002-84-2 | >98.00% | |
5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4. | ||||
| GC42548 | 5-hydroxy Saxagliptin (hydrochloride) | - | >95.00% | |
5-hydroxy Saxagliptin is a major active metabolite of saxagliptin. | ||||