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Mitophagy

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Mitophagy is the selective degradation of mitochondria by autophagy.

Mitochondria are essential organelles that regulate cellular energy homeostasis and cell death. The removal of damaged mitochondria through autophagy, a process called mitophagy, is thus critical for maintaining proper cellular functions. Indeed, mitophagy has been recently proposed to play critical roles in terminal differentiation of red blood cells, paternal mitochondrial degradation, neurodegenerative diseases, and ischemia or drug-induced tissue injury.

Autophagy and mitophagy are important cellular processes that are responsible for breaking down cellular contents, preserving energy and safeguarding against accumulation of damaged and aggregated biomolecules.

Products Related to Mitophagy(84)

  • GC71260 structure
    GC71260Dox-btn2
    CAS: 3026061-31-1
    Purity: >97.00%

    Dox-btn2 는 아마이신의 바이오매스 유도체로 3'-NH 2곳에서 아마이신과 결합할 때 바이오매스 표시를 하고 있다.

  • GC71423 structure
    GC71423ATTECs Degrader 1
    Purity: >95.00%

    ATTECs Degrader 1 (화합물 MT1)은 ATTEC 화합물입니다.

  • GC71451 structure
    GC71451MTX115325
    CAS: 2750895-97-5
    Purity: >99.00%

    MTX115325 (실시예 1) 는 신경보호 활성을 가진 경구용 활성, 뇌투과성 USP30 억제제(IC50 = 12nM)이다.

  • GC71492 structure
    GC71492WJ-39
    CAS: 3009908-95-3
    Purity: >99.00%

    WJ-39 는 경구용 활성알데히드당 환원효소(AR) 억제제다.

  • GC74187 structure
    GC74187Salicylic acid-13C6
    CAS: 1189678-81-6
    Purity: >97.00%

    Salicylic acid-13C6는 13c로 표기된 살리실산이다.

  • GC80919 structure
    GC80919AURKA-IN-4
    CAS: 89575-11-1
    Purity: >99.50%

    AURKA-IN-4 is a Capsaicin -derived molecular glue targeting AURKA-PHB2, and acts as an inhibitor of Aurora kinase A ( AURKA ) and PHB2.

  • GC81846 structure
    GC81846Nivitol
    CAS: 869743-37-3
    Purity: >98.00%

    Nivitol (UP302) is a natural phenolic compound discovered from Dianella ensifolia and also acts as a Tyrosinase inhibitor.

  • GN10156 structure
    GN10156Ginsenoside Rb1
    CAS: 41753-43-9
    Purity: >98.00%

    Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways.

  • GN10257 structure
    GN10257Naringin
    CAS: 10236-47-2
    Purity: >99.50%
  • GN10266 structure
    GN10266Quercetin
    CAS: 117-39-5
    Purity: >97.00%

    퀘르세틴은 채소, 과일, 씨앗, 견과류, 차 및 레드 와인에 포함된 중요한 식이 플라보노이드입니다.

  • GN10331 structure
    GN10331Polydatin
    CAS: 27208-80-6
    Purity: >98.00%

    Polydatin은Polygonum cuspidatum에서 추출된 천연 스틸베놀 글루코사이드이고 Polydatin은 레스베라트롤의 글리코사이드 형태이다.

  • GN10357 structure
    GN10357Parthenolide
    CAS: 20554-84-1
    Purity: >98.00%

    Parthenolide는 Eca109, KYSE-510, SiHa, MCF-7 세포에 대해 각각 약 10.3, 13.3, 8.42, 9.54μM의 IC50 값을 가지는 NF-κB 억제제이다(48시간).