ULK-101 |
| Catalog No.GC34315 |
ULK-101은 ULK1 및 ULK2에 대해 각각 1.6nM 및 30nM의 IC50 값을 갖는 강력하고 선택적인 ULK1 억제제입니다. ULK-101은 자가포식을 억제하고 암세포를 영양 스트레스에 민감하게 합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2443816-45-1
Sample solution is provided at 25 µL, 10mM.
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ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1.6 nM and 30 nM for ULK1 and ULK2 in vitro, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress[1].
[1]. Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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