GLPBio

Mefuparib

Catalog No.: GC83532Purity:>99.50%Synonyms: CVL218
COASDSData Sheet
Mefuparib (CVL218) is a poly ADP-ribose polymerase ( PARP ) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.

Products are for research use only. Not for human use. We do not sell to patients.

Mefuparib
Cas No.: 1392502-82-7
10mM (in 1mL DMSO)In Stock
$103.00
1
5mgIn Stock
$94.00
1
10mgIn Stock
$151.00
1
25mgIn Stock
$301.00
1
50mgIn Stock
$482.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Mefuparib (CVL218) is a poly ADP-ribose polymerase ( PARP ) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.

References:
[1]. Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats

Product Documents

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1392502-82-7
Synonyms
CVL218
Molecular Formula
C17H15FN2O2
Molecular Weight
298.31
Solubility
DMSO: 6.25 mg/mL (20.95 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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