ML-030 (Synonyms: CID-11757146) |
| Catalog No.GC16072 |
PDE4 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1013750-77-0
Sample solution is provided at 25 µL, 10mM.
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ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively.
ML-030 is potent in cell-based assay with an EC50 value of 18.7 nM[1].
References:
[1]. Skoumbourdis AP, et al. Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92.
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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