Muscarinic Receptor
Muscarinic receptor is a group of G-protein coupled receptors that binds to acetylcholine and mediates cellular responses, including inhibition of acetylate cyclase, phosphoinositide degradation and regulation of potassium channels. It is involved in the neurological diseases such as Alzheimer's and Parkinson's.
Products Related to Muscarinic Receptor(41)
- GC10621Biperiden HClCAS: 1235-82-1Purity: >98%
Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system.
- GC15772Darifenacin HBrCAS: 133099-07-7Purity: >98.00%
Darifenacin HBr (UK-88525 hydrobromide) is a selective M3 muscarinic receptor antagonist with pKi of 8.9.
- GC17954Tolterodine tartrateCAS: 124937-52-6Purity: >99.50%
Competitive muscarinic receptor antagonist
- GC10378N-IsopropylnoratropineCAS: 22235-81-0Purity: >98%
used in the synthesis of ipratropium, a muscarinic antagonist
- GC11415Arecaidine but-2-ynyl ester tosylateCAS: 119630-77-2Purity: >98.00%
Arecaidine but-2-ynyl ester tosylate is a selective muscarinic acetylcholine receptor (mAChR) M2 agonist.
- GC11831Umeclidinium bromideCAS: 869113-09-7Purity: >98.00%
A muscarinic acetylcholine receptor antagonist
- GC12311Trihexyphenidyl hydrochlorideCAS: 52-49-3Purity: >99.50%
antiparkinsonian agent of the antimuscarinic class
- GC13403Pirenzepine dihydrochlorideCAS: 29868-97-1Purity: >98.00%
M1 muscarinic receptor selective antagonist
- GC14215CevimelineCAS: 107233-08-9Purity: >98.00%
Cevimeline is a potent direct-acting muscarinic receptor agonist with oral bioavailability.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10621 | Biperiden HCl | 1235-82-1 | >98% | |
Biperiden (KL 373) hydrochloride is a non-selective muscarinic receptor antagonist that competitively binds to M1 muscarinic receptors, thereby inhibiting acetylcholine and enhancing dopamine signaling in the central nervous system. | ||||
| GC14096 | Aclidinium Bromide | 320345-99-1 | >98.00% | |
LAMAs antagonist | ||||
| GC15772 | Darifenacin HBr | 133099-07-7 | >98.00% | |
Darifenacin HBr (UK-88525 hydrobromide) is a selective M3 muscarinic receptor antagonist with pKi of 8.9. | ||||
| GC16087 | Fesoterodine Fumarate | 286930-03-8 | >98% | |
Muscarinic AChR receptor antagonist | ||||
| GC17182 | Solifenacin succinate | 242478-38-2 | >99.00% | |
Muscarinic receptor antagonist | ||||
| GC17954 | Tolterodine tartrate | 124937-52-6 | >99.50% | |
Competitive muscarinic receptor antagonist | ||||
| GC10219 | AF-DX 116 | 102394-31-0 | >99.50% | |
AF-DX 116 (AF-DX 116) is a selective and competitive M2 muscarinic acetylcholine receptor antagonist, with IC50 values of 640 nM and 386 nM for rabbit peripheral lung and rat heart, respectively. | ||||
| GC10378 | N-Isopropylnoratropine | 22235-81-0 | >98% | |
used in the synthesis of ipratropium, a muscarinic antagonist | ||||
| GC10464 | VU 0255035 | 1135243-19-4 | >98% | |
muscarinic M1 antagonist | ||||
| GC10525 | Nitrocaramiphen hydrochloride | 98636-73-8 | >98% | |
M1 muscarinic antagonist | ||||
| GC10633 | DAU 5884 hydrochloride | 131780-48-8 | >98% | |
muscarinic M3 receptor antagonist | ||||
| GC10725 | VU 10010 | 633283-39-3 | >98.50% | |
allosteric potentiator of M4 acetylcholine receptors | ||||
| GC10736 | (+)-Muscarine iodide | 24570-49-8 | >98% | |
Muscarinic acetylcholine receptor agonist | ||||
| GC11415 | Arecaidine but-2-ynyl ester tosylate | 119630-77-2 | >98.00% | |
Arecaidine but-2-ynyl ester tosylate is a selective muscarinic acetylcholine receptor (mAChR) M2 agonist. | ||||
| GC11831 | Umeclidinium bromide | 869113-09-7 | >98.00% | |
A muscarinic acetylcholine receptor antagonist | ||||
| GC12056 | J 104129 fumarate | 244277-89-2 | >98% | |
M3 muscarinic receptor antagonist | ||||
| GC12311 | Trihexyphenidyl hydrochloride | 52-49-3 | >99.50% | |
antiparkinsonian agent of the antimuscarinic class | ||||
| GC12787 | Aceclidine (hydrochloride) | 6109-70-2 | >95.00% | |
agonist of muscarinic receptors | ||||
| GC13129 | W-84 dibromide | 21093-51-6 | >98.00% | |
M2-receptor selective modulator | ||||
| GC13174 | Telenzepine dihydrochloride | 147416-96-4 | >98% | |
muscarinic M1 receptor antagonist | ||||
| GC13340 | AQ-RA 741 | 123548-16-3 | >98% | |
M2 antagonist,selective and high affinity | ||||
| GC13348 | 4-DAMP | 1952-15-4 | >95.00% | |
M3 cholinergic receptor antagonist | ||||
| GC13403 | Pirenzepine dihydrochloride | 29868-97-1 | >98.00% | |
M1 muscarinic receptor selective antagonist | ||||
| GC14215 | Cevimeline | 107233-08-9 | >98.00% | |
Cevimeline is a potent direct-acting muscarinic receptor agonist with oral bioavailability. | ||||