GLPBio

MXS

Catalog No.: GC48526Purity:>90.00%
A fluorescent probe for hypochlorous acid

Products are for research use only. Not for human use. We do not sell to patients.


MXS
1mgIn Stock
$180.00
1
5mgIn Stock
$424.00
1
10mgIn Stock
$656.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

MXS is a mitochondria-targeted fluorescent probe for hypochlorous acid (HOCl).1 It selectively fluoresces in the presence of OCl- over O2, H2O2, NO, NO2-, NO3-, O2-, ONOO-, and •OH when used at a concentration of 10 µM. MXS has been used to monitor real-time mitochondrial HOCl levels in living cells. It displays excitation/emission maxima of 530/654 nm, respectively.

1.Gong, J., Liu, C., Cai, S., et al.Novel near-infrared fluorescent probe with a large Stokes shift for sensing hypochlorous acid in mitochondriaOrg. Biomol. Chem.18(38)7656-7662(2020)

Product Documents

Purity:>90.00%Appearance:A solid

Chemical Properties

SMILES
CSC(C=C1)=CC=C1/C=C/C2=C3C(OC4=C2C=CC(OC)=C4)=C/C(C=C3)=[N+](CC)\CC
Molecular Formula
C27H28NO2S
Molecular Weight
430.6
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml,Ethanol: slightly soluble
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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