Negative Controls

4α-Phorbol 12-myristate 13-acetate is an inactive form of TPA, and is used as a negative control for TPA-activated events.

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM.

Terminal differentiation of embryonic progenitor cells to form distinct, adult tissues is the hallmark of organogenesis in complex organisms.

ABC34 is an inactive control probe for JJH260, the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs).

Dnp-GPLG is a peptide for use as a negative control for activity of matrix metalloproteinases (MMPs) that cleave peptides containing the sequence Dnp-GPLG.

GSK106 (hydrochloride) is an inactive control for the selective PAD4 inhibitors, GSK484 and GSK199.

The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer.

An inactive control for DO264

UNC7145 is an inactive derivative of the histone-lysine N-methyltransferase NSD2 inhibitor UNC6934 that has been used as a negative control for the histone methyltransferase activity of NSD2.