GLPBio

OX Receptor

OX receptor (orexin receptor) is a G-protein coupled receptor that is involved in the regulation of feeding behaviour.

Products Related to OX Receptor(52)

  • GC13539 structure
    GC13539SB-334867 hydrochloride
    CAS: 249889-64-3
    Purity: >98.00%

    SB-334867 hydrochloride is a potent, selective, and blood-brain barrier-permeable orexin-1 (OX1) receptor antagonist, with pK b of 7.4 for OX1 and pK i values of 5.4 and 5.3 for 5-HT2B and 5-HT2C, respectively.

  • GC15034 structure
    GC15034SB-334867
    CAS: 792173-99-0
    Purity: >98.00%

    SB-334867 is a potent, selective, and blood-brain barrier-permeable orexin-1 (OX1) receptor antagonist, with pK b of 7.4 for OX1 and pK i values of 5.4 and 5.3 for 5-HT2B and 5-HT2C, respectively.

  • GC15317 structure
    GC15317SB408124
    CAS: 288150-92-5
    Purity: >98.50%

    OX(1)receptor antagonist

  • GC17807 structure
    GC17807TCS 1102
    CAS: 916141-36-1
    Purity: >99.50%

    Antagonist for OX2 and OX1 receptors

  • GC10549 structure
    GC10549TCS OX2 29
    CAS: 372523-75-6
    Purity: >99.50%

    OX2 receptor antagonist

  • GC11818 structure
    GC11818OXA (17-33)
    CAS: 343268-91-7
    Purity: >98%

    orexin OX1 receptor agonist

  • GC12242 structure
    GC12242MK 6096
    CAS: 1088991-73-4
    Purity: >99.00%

    MK 6096 (MK-6096) is an orally bioavailable potent and selective reversible antagonist of OX1 and OX2 receptor(<3 nM in binding).

  • GC13741 structure
    GC13741EMPA
    CAS: 680590-49-2
    Purity: >99.50%

    OX2 receptor antagonist

  • GC14809 structure
    GC14809JNJ 10397049
    CAS: 708275-58-5
    Purity: >98.50%

    OX2 receptor antagonist

  • GC14887 structure
    GC14887Orexin B (human)
    CAS: 205640-91-1
    Purity: >98%

    Orexin B (human), a 28-residue peptides, has affinity for the OX1 and OX2 receptor with Ki of 420 and 36nM, respectively.

  • GC15534 structure
    GC15534SB-674042
    CAS: 483313-22-0
    Purity: >99.50%

    A potent and selective orexin 1 receptor antagonist

  • GC16336 structure
    GC16336ACT 335827
    CAS: 1354039-86-3
    Purity: >98%

    Orexin receptor 1 antagonist,potent and selective

  • GC16540 structure
    GC16540SB-408124 Hydrochloride
    CAS: 1431697-90-3
    Purity: >98.00%

    A potent orexin 1 receptor antagonist

  • GC16745 structure
    GC16745Orexin B (mouse)
    CAS: 202801-92-1
    Purity: >98.50%

    Orexin B (mouse) (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.

  • GC17992 structure
    GC17992[Ala11,D-Leu15]-Orexin B
    CAS: 532932-99-3
    Purity: >98%

    [Ala11,D-Leu15]-Orexin B is a potent and selective orexin-2 receptor (OX2) agonist.

  • GC19220 structure
    GC19220Lemborexant
    CAS: 1369764-02-2
    Purity: >99.50%

    Lemborexant (E2006) is an oral active diorexin receptor antagonist (DORA) and has been approved by the US Food and Drug Administration for the treatment of insomnia.

  • GC19249 structure
    GC19249MK-1064
    CAS: 1207253-08-4
    Purity: >99.50%

    MK-1064 is a selective orexin 2 receptor antagonist (2-SORA) for the research of insomnia.

  • GC19250 structure
    GC19250MK-3697
    CAS: 1224846-01-8
    Purity: >99.00%

    MK-3697 is an isonicotinamide small molecule, acting as a potent and selective Orexin 2 receptor antagonist with Ki = 0.95 nM.

  • GC19272 structure
    GC19272Orexin 2 Receptor Agonist
    CAS: 1796565-52-0
    Purity: >99.50%

    Orexin 2 Receptor Agonist is a potent (EC50 on OX2R is 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio is 70) agonist.

  • GC19323 structure
    GC19323SB-649868
    CAS: 380899-24-1
    Purity: >98%

    SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

  • GC30829 structure
    GC30829IPSU
    CAS: 1373765-19-5
    Purity: >98.00%

    An orexin receptor 2 antagonist

  • GC30832 structure
    GC30832GSK1059865
    CAS: 1191044-58-2
    Purity: >99.50%

    GSK1059865 is a potent orexin 1 receptor antagonist.

  • GC30941 structure
    GC30941Nemorexant (ACT-541468)
    CAS: 1505484-82-1
    Purity: >98.00%

    Nemorexant (ACT-541468), a benzimidazole derivative, is an orally selective dual-orexin antagonist (DORA).

  • GC36812 structure
    GC36812Orexin B, human TFA
    Purity: >98.00%

    Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.