Oxidative Phosphorylation

FCCP is a highly lipophilic mitochondrial uncoupler.

CCCP isa protonophore altering the permeability of mitochondria inner membrane to protons.

Rotenone is a mitochondrial electron transport chain complex I inhibitor that can induce apoptosis by enhancing the production of mitochondrial reactive oxygen species.

3-Nitropropionic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase.

BAM15 is a novel mitochondrial protonophore uncoupler (2-fluorophenyl){6-[(2-fluorophenyl)amino](1,2,5-oxadiazolo[3,4-e]pyrazin-5-yl)}amine, that does not depolarize the plasma membrane.

2-Thenoyltrifluoroacetone (TTFA) is an inhibitor of respiration in animals and bacteria.

DNP-INT is a quinone analog that inhibits electron transport in plants by competitively inhibiting plastoquinol oxidation by binding at the Qo site of cytochrome b6f (Kd = 1.4 nM).

An N-acyl amide

A broad-spectrum carboxamide fungicide

An endogenous N-acyl amine

A mitochondrial uncoupler

A bacterial metabolite with insecticidal and antimicrobial activities

An internal standard for the quantification of didanosine

A fungicide

A mitochondrial complex I inhibitor and an AMPKα activator

Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α1 (TRα1) inhibitor.

An active metabolite of benzbromarone

Mitochondrial fusion promoter M1, a cell-permeable phenylhydrazone, effectively promotes mitochondrial fusion.

Chlorfenapyr, a pyrrole insecticide that impairs mitochondrial activity.

TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor.

MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect.

Acetyl coenzyme A -d 3 (Acetyl-CoA-d 3 ) is the deuterium labeled Acetyl coenzyme A.

A reverse transcriptase inhibitor and an active metabolite of ddA and ddI

A mitochondrial complex I inhibitor