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Home >> Signaling Pathways >> Metabolism

Metabolism

  1. Cat.No. Product Name Information
  2. GC68479 MMRi62 MMRi62 Chemical Structure
  3. GC68460 PDE4B-IN-3 PDE4B-IN-3 Chemical Structure
  4. GC68450 Hsp90-IN-17 hydrochloride Hsp90-IN-17 hydrochloride Chemical Structure
  5. GC68445 SCD1 inhibitor-3 SCD1 inhibitor-3 Chemical Structure
  6. GC68325 Roflumilast-d4 N-Oxide Roflumilast-d4 N-Oxide Chemical Structure
  7. GC68317 (3S,5R)-Fluvastatin-d6 sodium (3S,5R)-Fluvastatin-d6 sodium Chemical Structure
  8. GC68229 PDE5-IN-7 PDE5-IN-7 Chemical Structure
  9. GC68133 Palmatine hydroxide Palmatine hydroxide Chemical Structure
  10. GC68041 Pentoxifylline-d5 Pentoxifylline-d5 Chemical Structure
  11. GC68034 Enoxaparin Enoxaparin Chemical Structure
  12. GC68003 Cadisegliatin Cadisegliatin Chemical Structure
  13. GC67997 Aminopeptidase-IN-1 Aminopeptidase-IN-1 Chemical Structure
  14. GC67967 Dovramilast Dovramilast Chemical Structure
  15. GC67933 LKY-047 LKY-047 Chemical Structure
  16. GC67916 Palmitic acid-d4 Palmitic acid-d4 Chemical Structure
  17. GC67909 GSK2647544 GSK2647544 Chemical Structure
  18. GC67901 Glucokinase activator 3 Glucokinase activator 3 Chemical Structure
  19. GC67894 FASN-IN-5 FASN-IN-5 Chemical Structure
  20. GC67866 PPARδ/γ agonist 1 sodium PPARδ/γ agonist 1 sodium Chemical Structure
  21. GC67864 (R)-Irsenontrine (R)-Irsenontrine Chemical Structure
  22. GC67714 DP00477 DP00477 Chemical Structure
  23. GC52513 Indolimine-214 A genotoxic gut microbiota metabolite Indolimine-214 Chemical Structure
  24. GC52504 Human Vitamin D Receptor Reporter Assay System A nuclear receptor cell-based reporter assay Human Vitamin D Receptor Reporter Assay System Chemical Structure
  25. GC52497 Lactosylceramide (porcine RBC) A sphingolipid Lactosylceramide (porcine RBC) Chemical Structure
  26. GC52496 Sulfatide (bovine) (sodium salt) A mixture of isolated bovine sulfatides Sulfatide (bovine) (sodium salt) Chemical Structure
  27. GC52493 Glucosylceramide (bovine buttermilk) A sphingolipid Glucosylceramide (bovine buttermilk) Chemical Structure
  28. GC52492 Globotriaosylceramide (hydroxy) (porcine RBC) A sphingolipid Globotriaosylceramide (hydroxy) (porcine RBC) Chemical Structure
  29. GC52491 Globotriaosylceramide (non-hydroxy) (porcine RBC) A sphingolipid Globotriaosylceramide (non-hydroxy) (porcine RBC) Chemical Structure
  30. GC52467 Cell Death Screening Library For screening a variety of cell death pathways Cell Death Screening Library Chemical Structure
  31. GC52462 Microbiome Metabolite Screening Library For screening a variety of microbiome metabolites Microbiome Metabolite Screening Library Chemical Structure
  32. GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid 10-oxo-12(Z)-Octadecenoic Acid-d5 Chemical Structure
  33. GC52421 (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 An internal standard for the quantification of (±)-10-hydroxy-12(Z)-octadecenoic acid (±)-10-hydroxy-12(Z)-Octadecenoic Acid-d5 Chemical Structure
  34. GC52420 Drospirenone-13C3 An internal standard for the quantification of drospirenone Drospirenone-13C3 Chemical Structure
  35. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  36. GC52409 BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) A neuropeptide and MRGPRX1 agonist BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt) Chemical Structure
  37. GC52404 γ-Glu-Phe (trifluoroacetate salt) A dipeptide with metabolism-altering activity γ-Glu-Phe (trifluoroacetate salt) Chemical Structure
  38. GC52400 γ-Glu-Ala (trifluoroacetate salt) A dipeptide γ-Glu-Ala (trifluoroacetate salt) Chemical Structure
  39. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate) An endogenous peptide and agonist of GAL2 and GAL3 Spexin 1 (human, mouse, rat, bovine) (acetate) Chemical Structure
  40. GC52384 NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) A cell-permeable form of NFAT inhibitor NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) Chemical Structure
  41. GC52376 BMP2-derived Peptide (trifluoroacetate salt) A synthetic peptide BMP2-derived Peptide (trifluoroacetate salt) Chemical Structure
  42. GC52361 AMARA Peptide (trifluoroacetate salt) A peptide substrate for AMPK AMARA Peptide (trifluoroacetate salt) Chemical Structure
  43. GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide Chemical Structure
  44. GC52329 Betamethasone-d5 An internal standard for the quantification of betamethasone Betamethasone-d5 Chemical Structure
  45. GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate A metabolite of certain phenols and glycosides 3-(3-Hydroxyphenyl)propionic Acid sulfate Chemical Structure
  46. GC52323 L-Isoleucine-13C6 An internal standard for the quantification of L-isoleucine L-Isoleucine-13C6 Chemical Structure
  47. GC52318 Oleic Acid-13C5 An internal standard for the quantification of oleic acid Oleic Acid-13C5 Chemical Structure
  48. GC52317 BCP-T.A. A ferroptosis inducer BCP-T.A. Chemical Structure
  49. GC52315 GK241 An sPLA2 (Type IIA) inhibitor GK241 Chemical Structure
  50. GC52304 Perfluoroheptanoic Acid A perfluoroalkyl substance Perfluoroheptanoic Acid Chemical Structure
  51. GC52290 (R)-HTS-3 An inhibitor of LPCAT3 (R)-HTS-3 Chemical Structure
  52. GC52278 Creatine Phosphate (sodium salt hydrate) A phosphorylated form of creatine Creatine Phosphate (sodium salt hydrate) Chemical Structure
  53. GC52257 Perfluorohexanoic Acid A perfluoroalkyl substance Perfluorohexanoic Acid Chemical Structure
  54. GC52253 α-Enolase (1-19)-biotin Peptide A biotinylated α-enolase peptide α-Enolase (1-19)-biotin Peptide Chemical Structure
  55. GC52251 Imidacloprid Impurity 1 A potential impurity in commercial preparations of imidacloprid Imidacloprid Impurity 1 Chemical Structure
  56. GC52231 Heptadecanoyl-L-carnitine-d3 (chloride) An internal standard for the quantification of heptadecanoyl-L-carnitine Heptadecanoyl-L-carnitine-d3 (chloride) Chemical Structure
  57. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone Chemical Structure
  58. GC52219 Heptadecanoyl-L-carnitine (chloride) A long-chain acylcarnitine Heptadecanoyl-L-carnitine (chloride) Chemical Structure
  59. GC52214 Nicotinamide riboside-d4 (triflate) An internal standard for the quantification of nicotinamide riboside Nicotinamide riboside-d4 (triflate) Chemical Structure
  60. GC67661 S-2E S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research. S-2E Chemical Structure
  61. GC67211 BAPTA tetrapotassium BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators. BAPTA tetrapotassium Chemical Structure
  62. GC66645 L-Adenosine L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation. L-Adenosine Chemical Structure
  63. GC66360 Girentuximab Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC). Girentuximab Chemical Structure
  64. GC66197 α-?Terpinyl acetate α-Terpinyl acetate is a monoterpene ester isolated from Laurus nobilis L. essential oil. α-Terpinyl acetate is a competitive P450 2B6 substrate which binding to the active site of P450 2B6 with a Kd value of 5.4 μM. α-?Terpinyl acetate Chemical Structure
  65. GC66059 YZ129 YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation. YZ129-induced GBM cell-cycle arrest at the G2/M phase promotes apoptosis and inhibited tumor cell proliferation and migration. YZ129 Chemical Structure
  66. GC66042 Enpp-1-IN-14 ENPP1-IN-2 is a potent Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) inhibitor with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity. Enpp-1-IN-14 Chemical Structure
  67. GC66029 hCAI/II-IN-6 hCAI/II-IN-6 is an orally active human carbonic anhydrase (CA) inhibitor. hCAI/II-IN-6 selectively inhibits hCA II and hCA VII isoforms with Ki values of 220, 4.9, 6.5 and ＞50000 nM for hCA I, hCA II , hCA VII and hCA XII respectively. hCAI/II-IN-6 shows anticonvulsant activity and anti maximal electroshock (MES) activity in vivo. hCAI/II-IN-6 can be used for the research of epilepsy. hCAI/II-IN-6 Chemical Structure
  68. GC66015 IHVR-11029 IHVR-11029 is a small molecule inhibitor of ER α-glucosidases, with an EC50 of 0.09 μM. IHVR-11029 Chemical Structure
  69. GC66005 CVT-11127 CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer. CVT-11127 Chemical Structure
  70. GC65925 TDP1 Inhibitor-1 TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM. TDP1 Inhibitor-1 Chemical Structure
  71. GC65912 Asundexian Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. Asundexian Chemical Structure
  72. GC65911 Irsenontrine Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 (PDE9) inhibitor. Irsenontrine can be used for the research of neurological diseases. Irsenontrine Chemical Structure
  73. GC65895 IDO1-IN-19 IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1. IDO1-IN-19 has the potential for the research of cancer diseases. IDO1-IN-19 Chemical Structure
  74. GC65612 Acetazolamide sodium Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX. Acetazolamide sodium has diuretic, antihypertensive and anti-gonococcal activities. Acetazolamide sodium Chemical Structure
  75. GC52194 Dimethylamino Parthenolide Dimethylamino Parthenolide Chemical Structure
  76. GC52190 Imidazole Ketone Erastin Imidazole Ketone Erastin Chemical Structure
  77. GC52189 Nomegestrol Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity. Nomegestrol Chemical Structure
  78. GC52170 2-Nitroamino-2-imidazoline 2-Nitroamino-2-imidazoline Chemical Structure
  79. GC52164 Cu-ATSP Cu-ATSP, a potent inhibitor of ferroptotic cell death, is almost 20-fold more potent than CuATSM. Cu-ATSP Chemical Structure
  80. GC52159 N-methyl Tyramine (hydrochloride) N-methyl Tyramine (hydrochloride) Chemical Structure
  81. GC52149 306-O12B 306-O12B Chemical Structure
  82. GC52139 NG-497 NG-497 Chemical Structure
  83. GC52138 Pantoic Acid Pantoic Acid Chemical Structure
  84. GC52129 3-Amino-5-hydroxybenzoic Acid 3-Amino-5-hydroxybenzoic Acid Chemical Structure
  85. GC52126 8-chloro Caffeine 8-chloro Caffeine Chemical Structure
  86. GC52125 T-1095 T-1095 is a selective and orally active Na+-glucose cotransporter (SGLT) inhibitor with IC50s of 22.8 ?M and 2.3 ?M for human SGLT1 and SGLT2, respectively. T-1095 Chemical Structure
  87. GC65595 3-Nitrocoumarin 3-Nitrocoumarin (3-NC) is a potent and selective Phospholipase C-γ (PLC-γ) inhibitor. 3-Nitrocoumarin Chemical Structure
  88. GC65549 Indisulam Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E. Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15. Indisulam Chemical Structure
  89. GC65517 4-(Trifluoromethyl)umbelliferone 4-(Trifluoromethyl)umbelliferone is fluorescent probe substrate for rat hepatic cytochrome P450 enzymes. 4-(Trifluoromethyl)umbelliferone Chemical Structure
  90. GC65499 IDO1/2-IN-1 hydrochloride IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active. IDO1/2-IN-1 hydrochloride Chemical Structure
  91. GC65426 CM-675 CM-675 is a dual phosphodiesterase 5 (PDE5) and class I histone deacetylases-selective inhibitor, with IC50 values of 114 nM and 673 nM for PDE5 and HDAC1, respectively. CM-675 Chemical Structure
  92. GC65414 2-(Tetradecylthio)acetic acid 2-Tetradecylthio acetic acid is a pan-peroxisome proliferator activated receptor (pan-PPAR) activator. 2-(Tetradecylthio)acetic acid Chemical Structure
  93. GC65409 7-Methylcoumarin 7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect. 7-Methylcoumarin Chemical Structure
  94. GC65360 PDE10-IN-5 PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders. PDE10-IN-5 Chemical Structure
  95. GC65345 BI 653048 BI 653048 is a selective and orally active nonsteroidal?glucocorticoid (GC)?agonist with an IC50 value of 55 nM. BI 653048 Chemical Structure
  96. GC65335 PTC299 PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies. PTC299 Chemical Structure
  97. GC65318 BOLD-100 BOLD-100 is a ruthenium-based anticancer agent. BOLD-100 also is an inhibitor of stress-induced GRP78 upregulation, disrupting endoplasmic reticulum (ER) homeostasis and inducing ER stress and unfolded protein response (UPR). BOLD-100 interferes with the complex interplay between ER-stress response, lysosome dynamics, and autophagy execution. BOLD-100 Chemical Structure
  98. GC65302 SDZ-MKS 492 SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 Chemical Structure
  99. GC65260 EDP-305 EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 Chemical Structure
  100. GC65258 PDE10A-IN-2 hydrochloride PDE10A-IN-2 hydrochloride is a potent, highly selective and orally active phosphodiesterase 10A (PDE10A) inhibitor with an IC50 of 2.8 nM. PDE10A-IN-2 hydrochloride Chemical Structure
  101. GC65246 Deltasonamide 2 Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM. Deltasonamide 2 Chemical Structure

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