GLPBio

PARP1-IN-56

Catalog No.: GC79061Purity:>99.00%
PARP1-IN-56 (Compound RCY) is an I-labeled poly(ADP−ribose) polymerase ( PARP1 ) inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.


PARP1-IN-56
Cas No.: 1574367-80-8
10mM (in 1mL DMSO)In Stock
$428.00
1
1mgIn Stock
$162.00
1
5mgIn Stock
$389.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

PARP1-IN-56 (Compound RCY) is an I-labeled poly(ADP−ribose) polymerase ( PARP1 ) inhibitor. PARP1-IN-56 can be radiolabeled with 211 At or 125 I for use as an α-emitting radiotherapeutic agent. PARP1-IN-56 can be used for the research of cancer [1].

References:
[1]. Reilly SW, et al. Rapid Cu-Catalyzed [ 211 At]Astatination and [ 125 I]Iodination of Boronic Esters at Room Temperature. Org Lett. 2018;20(7):1752-1755.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
1574367-80-8
Molecular Formula
C16H12IN3O
Molecular Weight
389.19
Solubility
DMSO: 20 mg/mL (51.39 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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