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PARP1-IN-56

Catalog No.GC79061 Copy One-Click Copy Product Info

PARP1-IN-56 (Compound RCY) is an I-labeled poly(ADP−ribose) polymerase ( PARP1 ) inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

PARP1-IN-56 Chemical Structure

Cas No.: 1574367-80-8

Size Price Stock Qty
10mM (in 1mL DMSO)
$428.00
In stock
1mg
$162.00
In stock
5mg
$389.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of PARP1-IN-56

PARP1-IN-56 (Compound RCY) is an I-labeled poly(ADP−ribose) polymerase ( PARP1 ) inhibitor. PARP1-IN-56 can be radiolabeled with 211 At or 125 I for use as an α-emitting radiotherapeutic agent. PARP1-IN-56 can be used for the research of cancer [1].

References:
[1]. Reilly SW, et al. Rapid Cu-Catalyzed [ 211 At]Astatination and [ 125 I]Iodination of Boronic Esters at Room Temperature. Org Lett. 2018;20(7):1752-1755.

Chemical Properties of PARP1-IN-56

Cas No. 1574367-80-8 SDF
Formula C16H12IN3O M.Wt 389.19
Solubility DMSO: 20 mg/mL (51.39 mM; ultrasonic and warming and heat to 60°C) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of PARP1-IN-56

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1 mg 5 mg 10 mg
1 mM 2.5694 mL 12.8472 mL 25.6944 mL
5 mM 513.9 μL 2.5694 mL 5.1389 mL
10 mM 256.9 μL 1.2847 mL 2.5694 mL
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In vivo Formulation Calculator (Clear solution) of PARP1-IN-56

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for PARP1-IN-56

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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