PEG diamine (Synonyms: PEG-bis-amine, Polyoxyethylene-bis-amine) |
| Catalog No.GC52107 |
A PEGylated building block
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 24991-53-5
Sample solution is provided at 25 µL, 10mM.
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PEG diamine is a PEGylated building block.1,2 It has been used as a linker to conjugate folic acid to 1,2-distearoyl-rac-glycero-PE (1,2-DSPE) as a component in the formation of doxorubicin-containing liposomes with anticancer activity.1 PEG diamine has also been conjugated to oleanolic acid , which improves oleanolic acid-induced inhibition of cell proliferation by 677-fold in HepG2 hepatocellular carcinoma cells.2
1.Lee, R.J., and Low, P.S.Folate-mediated tumor cell targeting of liposome-entrapped doxorubicin in vitroBiochim. Biophys. Acta1233(2)134-144(1995) 2.Jannus, F., Medina-O’Donnell, M., Rivas, F., et al.A diamine-PEGylated oleanolic acid derivative induced efficient apoptosis through a death receptor and mitochondrial apoptotic pathway in HepG2 human hepatoma cellsBiomolecules10(10)1375(2020)
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