Peptides

Dentonin (AC-100) is a short peptide fragment derived from MEPE. Dentonin promotes osteogenesis by promoting the adhesion of osteoprogenitor cells and can also promote the survival of immature adherent cells. Dentonin has no significant effect on mature bone-forming cells. Dentonin can be used for research on phosphate homeostasis and bone metabolism.

EGFRvIII peptide (PEPvIII) TFA is a tumor-specific mutation that is widely expressed in glioblastoma multiforme (GBM) and other tumors, and its expression enhances the incidence of tumors. EGFRvIII peptide (PEPvIII) TFA is a truly specific target for anti-tumor immunity.

Endotoxin inhibitor TFA is a synthetic peptide that can bind with high affinity to lipid A, detoxifying LPS and preventing the release of cytokines induced by LPS in vivo. Endotoxin inhibitor TFA can inhibit the fever response to LPS and has very low toxicity and mortality rates.

"[Glp1]-FGL peptide acetate" is a derivative of neural cell adhesion molecule (NCAM) and can be used for research on neurogenesis."

Fibrinogen-Binding Peptide TFA is a hypothetical peptide mimic of the fibrinogen receptor's von Willebrand factor binding site, designed based on the anti-integrin hypothesis. Fibrinogen-Binding Peptide TFA binds to fibrinogen, inhibiting platelet adhesion and aggregation to fibrinogen, as well as inhibiting platelet adhesion to fluothane.

G12 (Ras 5-17) is a wild-type Ras peptide composed of amino acids 5-17 (KLVVVGAGGVGKS). G12 can be used as a control for mutant Ras peptide research, such as V12.

"[Glu4]-Oxytocin acetate" is a derivative of oxytocin that can be used to comprehensively study the conformation of similar oxytocin molecules in aqueous solutions through various methods.

GRGDSPC TFA is a peptide containing 7 amino acids and is a thiol-modified cell adhesion peptide.

Histone H1-derived Peptide is a phosphorylated peptide substrate containing the sequence of CDK optimal recognition motif.

Human PD-L1 inhibitor I is a peptide ligand for hPD-1 with a KD value of 3.39 μM. It may interfere with the binding between hPD-L1 and hPD-1.

Insulin β Chain Peptide (15-23), also known as INS, is a pancreatic insulin-derived peptide recognized by islet-associated T cells. Insulin β Chain Peptide (15-23) tetramer stained INS-reactive CTL clone G9C8, but this tetramer did not stain NOD or 8.3-TCRαβ transgenic NOD mouse spleen CD8+ T cells compared to the negative control tetramer (TUM).

Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA is a 20 amino acid peptide and a major pathogenic epitope found in the first homologous repeat of the interphotoreceptor retinoid-binding protein peptide (IRBP 161-180), which is present in photoreceptors. It can cause experimental autoimmune uveitis (EAU).

Mad1 (6-21) is a 6-21 amino acid fragment of the Mad1 protein. Mad1 (6-21) binds to mammalian Sin3A PAH2 with a Kd of approximately 29 nM.

Mazdutide is a long-acting dual agonist of the glucagon-like peptide-1 receptor (GLP-1R; K i =28.6nM) and the glucagon receptor (GCGR; K i =17.7nM).

MPG peptides, Pβ is an amphipathic peptide composed of three structural domains.

MUC1, mucin core refers to the core region of MUC1 mucin protein. MUC1 is a type I transmembrane glycoprotein that is overexpressed and glycosylated in cancer cells. MUC1, mucin core binds to domain 1 of ICAM-1.

Myelin Basic Protein (87-99) TFA is a brain-specific peptide that can induce proliferation of alkaline protein-specific T cells. Myelin Basic Protein (87-99) TFA causes Th1 polarization in peripheral blood mononuclear cells and is associated with multiple sclerosis (MS).

NOTA-AE105 is a PET ligand for urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled with 64Cu and 68Ga. The images of 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 have high contrast and clear tumor delineation.

OVA (55-62) is a fragment derived from ovalbumin that can bind to mouse MHC class I molecule H2-Kb.

Oxytocin antiparallel dimer is a disulfide-linked homodimer. Oxytocin dimer has oxytocin and vasopressin-like activity, and its toxicity is lower than that of oxytocin.

Oxytocin free acid (9-Deamidooxytocin) TFA is an analogue of oxytocin, where the glycine residue at position 9 is replaced by another glycine residue. Oxytocin is a multifunctional peptide hormone that has broad effects on general health, adaptation, development, reproduction and social behavior.

Oxytocin parallel dimer is a disulfide-linked homodimer. Oxytocin dimer has oxytocin and vasopressin-like activity, and its toxicity is lower than that of oxytocin.

PAMP-12 (unmodified) is an effective MRGPRX2 (MrgX2) agonist (EC50=20-50 nM). PAMP-12 (unmodified) is an endogenous peptide that causes hypotension by inhibiting the release of catecholamines from sympathetic nerve endings and adrenal chromaffin cells.

Peripheral Myelin Protein P2 (53-78), bovine is a peptide derived from amino acid residues 53-78 of the bovine peripheral myelin protein P2. It is a T-cell antigenic epitope that can induce experimental autoimmune neuritis (EAN) in Lewis rats.